Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.42 |
| ▸ | HTR2A | P28223 | 8/20 | 0.41 |
| ▸ | HTR7 | P34969 | 5/20 | 0.41 |
| ▸ | DRD2 | P14416 | 8/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28313363 | 0.86 | HTR6 (0.53) | HTR6HTR2AHTR7DRD2CYP3A4 | |
| SCHEMBL28312482 | 0.74 | HTR6 (0.48) | HTR6HTR2AHTR7DRD2CYP3A4 | |
| SCHEMBL26967514 | 0.74 | HTR6 (0.41) | HTR6HTR2AHTR7DRD2 | |
| SCHEMBL28862184 | 0.73 | HTR6 (0.46) | HTR6HTR2AHTR7DRD2CYP3A4 | |
| SCHEMBL29993908 | 0.73 | HTR6 (0.46) | HTR6HTR2AHTR7DRD2CYP3A4 | |
| SCHEMBL6039554 | 0.72 | HTR6 (0.58) | HTR6HTR2AHTR7DRD2CYP3A4 | |
| SCHEMBL29429815 | 0.72 | HTR6 (0.56) | HTR6HTR2AHTR7DRD2CYP3A4 | |
| SCHEMBL6039811 | 0.72 | HTR6 (0.56) | HTR6HTR2AHTR7DRD2CYP3A4 | |
| SCHEMBL6039808 | 0.70 | HTR6 (0.55) | HTR6HTR2AHTR7DRD2CYP3A4 | |
| SCHEMBL20190392 | 0.70 | HTR6 (0.54) | HTR6HTR2AHTR7DRD2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484871-B1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS INC (US) | 2023-06-07 | — | — | EP | disclosed |