Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31379113 | 0.77 | JAK2 (0.32) | JAK2BTK | |
| SCHEMBL2524662 | 0.74 | TSHR (0.43) | CA1CA2CA9 | |
| SCHEMBL31379104 | 0.73 | LPL (0.34) | JAK2BTK | |
| SCHEMBL23357823 | 0.73 | PKM (0.46) | CA1CA2CA9 | |
| SCHEMBL22366946 | 0.72 | KCNH2 (0.33) | JAK2BTK | |
| SCHEMBL1130339 | 0.72 | TSHR (0.49) | CA1CA2CA9 | |
| SCHEMBL10325839 | 0.71 | EPHX1 (0.39) | CXCR2CA1CA2CA9 | |
| SCHEMBL4468874 | 0.71 | ALDH1A1 (0.44) | UCHL1CA1CA2CA9 | |
| SCHEMBL29734873 | 0.71 | ALDH1A1 (0.44) | UCHL1CA1CA2CA9 | |
| SCHEMBL25600203 | 0.71 | MAPT (0.41) | CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3814331-B1 | NOVEL LXR MODULATORS WITH BICYCLIC CORE MOIETY | ORSOBIO INC (US) | 2023-06-14 | — | — | EP | disclosed |