Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25549318 | 0.90 | KDM4E (0.45) | ALDH1A1HPGDTDP1SLC6A2SLC6A15 | |
| SCHEMBL21474580 | 0.82 | SLC6A3 (0.44) | ALDH1A1HPGDSLC6A2KDM4EKMT2A | |
| SCHEMBL25598740 | 0.74 | MAPK14 (0.45) | ALDH1A1HPGDTDP1TSHRMAPK14 | |
| SCHEMBL15675574 | 0.71 | ALDH1A1 (0.62) | ALDH1A1HPGDTDP1ESR1CHRM1 | |
| SCHEMBL21478257 | 0.70 | ALDH1A1 (0.49) | ALDH1A1HPGDTDP1KDM4ELMNA | |
| SCHEMBL21474573 | 0.69 | ALDH1A1 (0.41) | ALDH1A1HPGDTDP1TSHRSLC6A15 | |
| SCHEMBL21474668 | 0.69 | POLB (0.39) | ALDH1A1HPGDTDP1SLC6A15KDM4E | |
| SCHEMBL20267208 | 0.69 | ALDH1A1 (0.54) | ALDH1A1HPGDTDP1ESR1CHRM1 | |
| SCHEMBL10487722 | 0.69 | ALDH1A1 (0.54) | ALDH1A1HPGDTDP1ESR1CHRM1 | |
| SCHEMBL12447830 | 0.69 | SLC6A3 (0.44) | ALDH1A1HPGDSLC6A2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159439-A1 | ARYLAMIDES AND METHODS OF USE THEREOF | GENZYME CORPORATION | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159439-A1 | ARYLAMIDES AND METHODS OF USE THEREOF | CFTR, AADAC, ARSA | ALDH1A1 1072/4885HPGD 1090/4885TDP1 3414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.