Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | ADH1B | P00325 | 2/20 | 0.38 |
| ▸ | ADH1C | P00326 | 2/20 | 0.38 |
| ▸ | ADH1A | P07327 | 2/20 | 0.38 |
| ▸ | ADH4 | P08319 | 2/20 | 0.38 |
| ▸ | ADH7 | P40394 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22755788 | 0.86 | ACE2 (0.40) | ACE2LMNAEPHX1ADH1BADH1C | |
| SCHEMBL17088076 | 0.85 | TSHR (0.39) | EPHX1ADH1BADH1CADH1AALDH1A1 | |
| SCHEMBL19423383 | 0.84 | OPRM1 (0.45) | ACE2LMNAADH1BADH1CADH1A | |
| SCHEMBL24764379 | 0.82 | LMNA (0.39) | ACE2LMNAEPHX1ADH1BADH1C | |
| SCHEMBL25881999 | 0.82 | LMNA (0.39) | ACE2LMNAEPHX1ADH1BADH1C | |
| SCHEMBL22854544 | 0.81 | ACE2 (0.47) | ACE2LMNAEPHX1ADH1BADH1C | |
| SCHEMBL21509216 | 0.81 | TSHR (0.48) | ACE2LMNAEPHX1ADH1BADH1C | |
| SCHEMBL24673884 | 0.81 | ACE2 (0.47) | ACE2LMNAEPHX1ADH1BADH1C | |
| SCHEMBL22701029 | 0.81 | ACE2 (0.47) | ACE2LMNAEPHX1ADH1BADH1C | |
| SCHEMBL12512079 | 0.81 | ADH1B (0.44) | ACE2LMNAEPHX1ADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4194457-A1 | COMPOUND FOR TARGETING AND DEGRADING PROTEIN, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Leadingtac Pharmaceutical Co., Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |