SCHEMBL25600438

SCHEMBL25600438

CCC1(CC)c2ccccc2-c2c1c1c(c3cc(N4CCOCC4)ccc23)OC(c2ccc(OC)cc2)(c2ccc(OC)cc2)C=C1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.35
HTR7 P34969 1/20 0.33
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
ADAM17 P78536 1/20 0.33
ATM Q13315 1/20 0.33
FAAH O00519 1/20 0.33
PRKDC P78527 2/20 0.33
AKR1C3 P42330 1/20 0.32
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
HPGD P15428 1/20 0.32
CASP1 P29466 1/20 0.32
CASP7 P55210 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PDK2 Q15119 1/20 0.32
MAPT P10636 2/20 0.32
NPC1 O15118 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25600434 1.00 RAB9A (0.35) RAB9AHTR7MEN1KMT2AADAM17
SCHEMBL25606852 0.98 MAPT (0.34) RAB9AHTR7MEN1KMT2AADAM17
SCHEMBL25600300 0.97 RAB9A (0.35) RAB9AHTR7KMT2AADAM17ATM
SCHEMBL25607261 0.96 PRKDC (0.35) RAB9AMEN1KMT2AATMPRKDC
SCHEMBL25844668 0.96 ADAM17 (0.35) RAB9AHTR7MEN1KMT2AADAM17
SCHEMBL25844662 0.95 ADAM17 (0.34) RAB9AHTR7KMT2AADAM17ATM
SCHEMBL26627990 0.94 RAB9A (0.36) RAB9AHTR7KMT2AADAM17PRKDC
SCHEMBL25600437 0.94 PDK2 (0.35) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL26627907 0.93 MAPT (0.33) RAB9AHTR7MEN1KMT2AADAM17
SCHEMBL25844678 0.93 PDK2 (0.34) PRKDCKDM4EALDH1A1HPGDPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4269532-A1 PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES Hoya Lens Thailand Ltd. (TH) 2023-11-01 EP disclosed
US-20230340318-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES HOYA LENS THAILAND LTD. (TH) 2023-10-26 US disclosed
US-20230340318-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES HOYA LENS THAILAND LTD. (TH) 2023-10-26 US disclosed
US-20230227717-A1 PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND SPECTACLES HOYA LENS THAILAND LTD. (TH) 2023-07-20 US disclosed
US-20230227717-A1 PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND SPECTACLES HOYA LENS THAILAND LTD. (TH) 2023-07-20 US disclosed
EP-4198102-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES Hoya Lens Thailand Ltd. (TH) 2023-06-21 EP disclosed
EP-4198583-A1 PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND SPECTACLES Hoya Lens Thailand Ltd. (TH) 2023-06-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230340318-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES NR2E3, CRY1, RPS10 RAB9A 1795/4885HTR7 1788/4885MEN1 2472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.