SCHEMBL25600768

SCHEMBL25600768

CCC1(CC)c2cc(-c3ccccc3)ccc2-c2c1c1c(c3ccccc23)OC(c2ccc(OC)cc2)(c2ccc(OC)cc2)C=C1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 2/20 0.34
ACACA Q13085 1/20 0.33
PDK2 Q15119 1/20 0.33
ABL1 P00519 1/20 0.31
ABCB1 P08183 1/20 0.31
BCR P11274 1/20 0.31
EDNRB P24530 1/20 0.31
EDNRA P25101 1/20 0.31
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
MEN1 O00255 1/20 0.30
POLB P06746 1/20 0.30
KMT2A Q03164 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
LMNA P02545 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25600433 0.96 PDK2 (0.32) GPR84ACACAPDK2EDNRBEDNRA
SCHEMBL26627753 0.93 PDE10A (0.32) GPR84PDK2EDNRBEDNRA
SCHEMBL25599871 0.92 PDE10A (0.32) PDK2EDNRBEDNRA
SCHEMBL26627892 0.91 PDK2 (0.30) PDK2
SCHEMBL25600769 0.91 PRKDC (0.38) RAB9AMEN1KMT2AL3MBTL1LMNA
SCHEMBL25600131 0.90
SCHEMBL29565715 0.90 ESR1 (0.34) GPR84PDK2ABL1ABCB1BCR
SCHEMBL9898733 0.90 ESR1 (0.34) GPR84PDK2ABL1ABCB1BCR
SCHEMBL26629616 0.90 PDK2 (0.33) GPR84PDK2EDNRBEDNRARAB9A
SCHEMBL26512791 0.89 ACACA (0.38) GPR84ACACAPDK2KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230340318-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES HOYA LENS THAILAND LTD. (TH) 2023-10-26 US disclosed
US-20230340318-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES HOYA LENS THAILAND LTD. (TH) 2023-10-26 US disclosed
EP-4198102-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES Hoya Lens Thailand Ltd. (TH) 2023-06-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230340318-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES NR2E3, CRY1, RPS10 GPR84 1058/4885ACACA 2201/4885PDK2 2722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.