SCHEMBL25600433

SCHEMBL25600433

CCC1(CC)c2cc(-c3ccccc3)ccc2-c2c1c1c(c3cc(OC)ccc23)OC(c2ccc(OC)cc2)(c2ccc(OC)cc2)C=C1

nearest known ligand 0.32

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.32
EDNRB P24530 1/20 0.31
EDNRA P25101 1/20 0.31
GPR84 Q9NQS5 1/20 0.31
PIN1 Q13526 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
CYP2C9 P11712 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
CYP2C19 P33261 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30
HSD17B10 Q99714 1/20 0.30
ACACA Q13085 1/20 0.30
BACE1 P56817 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25600768 0.96 GPR84 (0.34) PDK2EDNRBEDNRAGPR84MEN1
SCHEMBL29565715 0.93 ESR1 (0.34) PDK2EDNRBEDNRAGPR84MEN1
SCHEMBL9898733 0.93 ESR1 (0.34) PDK2EDNRBEDNRAGPR84MEN1
SCHEMBL26627753 0.92 PDE10A (0.32) PDK2EDNRBEDNRAGPR84
SCHEMBL25600307 0.92 PIN1 (0.31) EDNRBEDNRAGPR84PIN1KDM4E
SCHEMBL26513197 0.92 BRD4 (0.32) GPR84KDM4EMEN1ALDH1A1LMNA
SCHEMBL25599871 0.92 PDE10A (0.32) PDK2EDNRBEDNRA
SCHEMBL25600545 0.91 PRKDC (0.35) KDM4EMEN1ALDH1A1LMNATSHR
SCHEMBL25600427 0.91 KDM4E (0.34) KDM4EMEN1ALDH1A1LMNACYP2C9
SCHEMBL26627892 0.90 PDK2 (0.30) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230340318-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES HOYA LENS THAILAND LTD. (TH) 2023-10-26 US disclosed
US-20230340318-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES HOYA LENS THAILAND LTD. (TH) 2023-10-26 US disclosed
EP-4198102-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES Hoya Lens Thailand Ltd. (TH) 2023-06-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230340318-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES NR2E3, CRY1, RPS10 PDK2 2722/4885EDNRB 1824/4885EDNRA 2402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.