⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19677275 | 0.86 | KDM4E (0.40) | — | |
| SCHEMBL8284899 | 0.80 | — | — | |
| SCHEMBL45854 | 0.80 | — | — | |
| SCHEMBL8671567 | 0.78 | MMP8 (0.46) | — | |
| SCHEMBL190205 | 0.76 | — | — | |
| SCHEMBL25080869 | 0.75 | HTT (0.42) | — | |
| SCHEMBL12768200 | 0.75 | FFAR1 (0.40) | — | |
| SCHEMBL8449242 | 0.75 | TAAR1 (0.45) | — | |
| SCHEMBL282133 | 0.74 | — | — | |
| SCHEMBL5260460 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240024305-A1 | METHODS AND COMPOSITIONS FOR TREATING RETINA-ASSOCIATED DISEASE USING CCR3-INHIBITORS | ALKAHEST, INC. | 2024-01-25 | — | — | US | disclosed |
| EP-4273147-A1 | SUBSTITUTED SPIROLACTAMS, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2023-11-08 | — | — | EP | disclosed |
| US-20230346764-A1 | Methods and Compositions for Treating Pruritus, Xerosis, and Associated Disease Using CCR3-Inhibitors | ALKAHEST, INC. | 2023-11-02 | — | — | US | disclosed |
| US-20230339913-A1 | SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS | NURA BIO, INC. | 2023-10-26 | — | — | US | disclosed |
| US-11771738-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2023-10-03 | — | — | US | disclosed |
| US-11737463-B2 | Pyridine and pyrazine compounds | BASF SE (DE) | 2023-08-29 | — | — | US | disclosed |
| US-11586060-B2 | Optical filter with light source | SOLUTIA CANADA INC. (CA) | 2023-02-21 | — | — | US | disclosed |
| US-20230045960-A1 | SUBSTITUTED HETEROAROMATIC PYRAZOLO-PYRIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-02-16 | — | — | US | disclosed |
| US-20230043959-A1 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS | INCYTE CORPORATION | 2023-02-09 | — | — | US | disclosed |
| EP-3842420-B1 | HETEROARYL INHIBITORS OF PDE4 | TETRA DISCOVERY PARTNERS LLC (US) | 2022-12-07 | — | — | EP | disclosed |
| EP-0008077-B1 | PROSTAGLANDIN DERIVATIVES WITH A DELTA-2-PGF2 STRUCTURE OR A DELTA-2-PGE2 STRUCTURE, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-11-16 | — | — | EP | disclosed |
| EP-0065200-A2 | Thiolactime ethers of delta-1-pyrrolidine, and their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-11-24 | — | — | EP | disclosed |
| EP-0055851-A1 | 11-Deoxy-hetero-imino-prostacyclins, processes for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-07-14 | — | — | EP | disclosed |
| US-4312882-A | ANTICOAGULANTS, HYPOTENSIVE AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-01-26 | — | — | US | disclosed |
| US-4304783-A | ANTITHROMBOTIC, ANTIINFARCT, HYPOTENSIVE AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-12-08 | — | — | US | disclosed |
| US-4296121-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-10-20 | — | — | US | disclosed |
| EP-0029527-A2 | Prostaglandin derivatives of the 6-keto-PGA1 series, process for their production as well as their use in medicaments and their intermediate products | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-06-03 | — | — | EP | disclosed |
| EP-0019069-A2 | 6-Keto PGE1 compounds, their preparation and therapeutic application, PGI1 compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-11-26 | — | — | EP | disclosed |
| EP-0013955-A1 | Analogues of prostacyclin, their intermediates, a process for their preparation and medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-08-06 | — | — | EP | disclosed |
| EP-0008077-A2 | Prostaglandin derivatives with a delta-2-PGF2 structure or a delta-2-PGE2 structure, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-02-20 | — | — | EP | disclosed |