SCHEMBL190205

SCHEMBL190205

ClCc1ccc(Cl)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1258558 0.82
SCHEMBL8671567 0.80 MMP8 (0.46)
SCHEMBL256014 0.76
SCHEMBL1372325 0.76
SCHEMBL2283138 0.76
SCHEMBL7012372 0.76
SCHEMBL353636 0.76
Hydrochloric Acid SCHEMBL719171 0.74
SCHEMBL11233527 0.74 ALDH1A1 (0.40)
SCHEMBL4526544 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 726 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116284046-A Ballon Sha Wei derivative, and preparation method and application thereof 山东新华制药股份有限公司 2023-06-23 CN claimed
EP-0081384-B1 PROCESS FOR THE PREPARATION OF AROMATIC OR HETEROAROMATIC CARBOXYLATED COMPOUNDS Montedison S.p.A. (IT) 1986-04-02 EP claimed
EP-0081384-A1 Process for the preparation of aromatic or heteroaromatic carboxylated compounds Montedison S.p.A. (IT) 1983-06-15 EP claimed
JP-1009987-A None JP disclosed
EP-4271674-B9 CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS GILEAD SCIENCES INC (US) 2026-03-11 EP disclosed
EP-4673137-A1 NBD1 MODULATORS AND METHODS OF USING THE SAME Sionna Therapeutics Inc. (US) 2026-01-07 EP disclosed
EP-4271674-B3 CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS GILEAD SCIENCES INC (US) 2025-12-03 EP disclosed
US-20250312352-A1 GLP-1R MODULATING COMPOUNDS GILEAD SCIENCES, INC. 2025-10-09 US disclosed
US-20250115606-A1 HETEROCYCLIC GLP-1 AGONISTS GASHERBRUM BIO, INC. 2025-04-10 US disclosed
EP-4520393-A2 CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS Gilead Sciences, Inc. (US) 2025-03-12 EP disclosed
EP-4271674-B1 CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS GILEAD SCIENCES INC (US) 2025-02-12 EP disclosed
EP-0112704-A2 Pyridine derivatives SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1984-07-04 EP disclosed
EP-0003560-B1 IMIDAZOLE DERIVATIVES AND SALTS THEREOF, THEIR SYNTHESIS, AND PHARMACEUTICAL FORMULATIONS THE WELLCOME FOUNDATION LIMITED (GB) 1984-05-02 EP disclosed
US-4416895-A ANTICOAGULANTS, ANTISHOCK AGENTS BURROUGHS WELLCOME CO. (US) 1983-11-22 US disclosed
EP-0081384-A1 Process for the preparation of aromatic or heteroaromatic carboxylated compounds Montedison S.p.A. (IT) 1983-06-15 EP disclosed
US-4272545-A FUNGICIDES, BACTERICIDE, ANTIPROTOZOA, SPERMATOCIDE SYNTEX (U.S.A.) INC. (US) 1981-06-09 US disclosed
EP-0003560-A2 Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations THE WELLCOME FOUNDATION LIMITED (GB) 1979-08-22 EP disclosed
US-4075340-A ANTIINFLAMMATORY, ANTIARRYTHMIC, ANTICOAGULANTS PARCOR (FR) 1978-02-21 US disclosed
US-4071533-A Phosphoramidates and thiophosphoramidates as pesticides ABBOTT LABORATORIES (US) 1978-01-31 US disclosed
US-3969526-A Anthelmintic 5-heterocycliothio and oxy-2-carbalkoxyaminobenzimidazles SMITHKLINE CORPORATION (US) 1976-07-13 US disclosed