SCHEMBL282133

SCHEMBL282133

OCc1ccc(Cl)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4393304 0.86 ALDH1A1 (0.55)
SCHEMBL4526544 0.80
SCHEMBL2229904 0.80
SCHEMBL8671567 0.78 MMP8 (0.46)
SCHEMBL190205 0.76
SCHEMBL256014 0.74
SCHEMBL1372325 0.74
SCHEMBL4590565 0.74
SCHEMBL353636 0.74
SCHEMBL7012372 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120115140-A Ultralow-temperature environment-friendly denitration catalyst and preparation method and application thereof 河北中增智能科技有限公司 2025-06-10 CN claimed
EP-4271674-B9 CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS GILEAD SCIENCES INC (US) 2026-03-11 EP disclosed
EP-4673137-A1 NBD1 MODULATORS AND METHODS OF USING THE SAME Sionna Therapeutics Inc. (US) 2026-01-07 EP disclosed
EP-4271674-B3 CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS GILEAD SCIENCES INC (US) 2025-12-03 EP disclosed
US-20250312352-A1 GLP-1R MODULATING COMPOUNDS GILEAD SCIENCES, INC. 2025-10-09 US disclosed
US-12404265-B2 Substituted pyridine derivatives as SARM1 inhibitors NURA BIO, INC. (US) 2025-09-02 US disclosed
CN-120115140-A Ultralow-temperature environment-friendly denitration catalyst and preparation method and application thereof 河北中增智能科技有限公司 2025-06-10 CN disclosed
WO-2025060978-A1 TRICYCLIC PYRIDINE COMPOUND ACTING AS SARM1 ENZYME ACTIVITY INHIBITOR, AND USE THEREOF 科辉智药(深圳)新药研究中心有限公司 2025-03-27 WO disclosed
US-20250101012-A1 HETEROCYCLE SUBSTITUTED PYRIDINE DERIVATIVE ANTIFUNGAL AGENTS BASILEA PHARMACEUTICA INTERNATIONAL AG, ALLSCHWIL (CH) 2025-03-27 US disclosed
EP-4520393-A2 CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS Gilead Sciences, Inc. (US) 2025-03-12 EP disclosed
WO-1998000389-A1 2-HYDROXYPROPIONIC ACID DERIVATIVE AND ITS MANUFACTURING METHOD JEW SANG SUP (KR) 1998-01-08 WO disclosed
WO-1998000422-A1 OXIRANE CARBOXYLIC ACID DERIVATIVE AND ITS MANUFACTURING METHOD JEW SANG SUP (KR) 1998-01-08 WO disclosed
WO-1997020843-A1 PYRIMIDINE DERIVATIVES AND GUANINE DERIVATIVES, AND THEIR USE IN TREATING TUMOUR CELLS CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 1997-06-12 WO disclosed
US-5266703-A Optically active isoxazole derivatives DAISO CO., LTD. (JP) 1993-11-30 US disclosed
US-5220074-A Optically active isoxazole derivatives and intermediates for preparation thereof as well as processes for producing the same DAISO CO., LTD. (JP) 1993-06-15 US disclosed
EP-0439129-A2 Optically active isoxazole derivatives and intermediates for preparation thereof as well as processes for producing the same Daiso Co., Ltd. (JP) 1991-07-31 EP disclosed
EP-0034778-B1 HETERO-IMINO-PROSTACYCLINS AND PROCESS FOR THEIR PREPARATION HOECHST AKTIENGESELLSCHAFT (DE) 1984-04-25 EP disclosed
US-4371542-A Hetero-imino-prostacyclins HOECHST AKTIENGESELLSCHAFT (DE) 1983-02-01 US disclosed
EP-0034778-A1 Hetero-imino-prostacyclins and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1981-09-02 EP disclosed
EP-0019069-A2 6-Keto PGE1 compounds, their preparation and therapeutic application, PGI1 compounds HOECHST AKTIENGESELLSCHAFT (DE) 1980-11-26 EP disclosed