SCHEMBL25601966

SCHEMBL25601966

C=C/C(=C\C=C/C)P(=O)(c1ccccc1)c1cccc(-c2cccc(-c3nc(-c4cccc(Cl)c4)nc(-c4cccc(Cl)c4)n3)c2)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1I3 Q14994 1/20 0.37
PDE4B Q07343 8/20 0.34
PDE4D Q08499 4/20 0.34
HDAC1 Q13547 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33
GRM5 P41594 1/20 0.33
ADORA1 P30542 2/20 0.32
ADORA3 P0DMS8 1/20 0.32
ADORA2A P29274 1/20 0.32
GSTO1 P78417 1/20 0.32
CNR2 P34972 1/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
DHPS P49366 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22335663 0.78 TSHR (0.42) LMNAL3MBTL1
SCHEMBL26077738 0.76 ALOX15 (0.31) L3MBTL1
SCHEMBL26077870 0.74 L3MBTL1 (0.33) CYP2C19GRM5ADORA1ADORA3ADORA2A
SCHEMBL20627786 0.74 ALOX15 (0.31)
SCHEMBL20565909 0.73 NR1I3 (0.44) NR1I3PDE4BPDE4DHDAC1HDAC6
SCHEMBL30452071 0.73 NR1I3 (0.44) NR1I3PDE4BPDE4DHDAC1HDAC6
SCHEMBL19999958 0.71 LMNA (0.31) LMNA
SCHEMBL25551056 0.68 NR1I3 (0.39) NR1I3PDE4BPDE4DLMNANPC1
SCHEMBL15683875 0.68 NR1I3 (0.54) NR1I3ADORA1ADORA2ANPC1RAB9A
SCHEMBL19917000 0.68 NR1I3 (0.54) NR1I3ADORA1ADORA2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4194442-A1 ORGANIC ELECTRONIC DEVICE COMPRISING AN ORGANIC SEMICONDUCTOR LAYER Novaled GmbH (DE) 2023-06-14 EP disclosed