Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 16/20 | 0.44 |
| ▸ | NOS1 | P29475 | 13/20 | 0.42 |
| ▸ | NOS3 | P29474 | 9/20 | 0.42 |
| ▸ | PTGES | O14684 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15329591 | 0.88 | CNR1 (0.38) | NOS2NOS1PTGESALOX5 | |
| SCHEMBL2558386 | 0.88 | TNKS2 (0.40) | NOS2NOS1NOS3 | |
| SCHEMBL2551809 | 0.86 | PTGES (0.36) | NOS2NOS1NOS3PTGESALOX5 | |
| SCHEMBL15331079 | 0.83 | PARP1 (0.35) | NOS2NOS1NOS3 | |
| SCHEMBL15331517 | 0.83 | PARP1 (0.36) | — | |
| SCHEMBL2558435 | 0.83 | APOL1 (0.37) | PTGESALOX5 | |
| SCHEMBL15330074 | 0.82 | DYRK1A (0.43) | PTGESALOX5 | |
| SCHEMBL2555217 | 0.82 | APOL1 (0.34) | NOS2 | |
| SCHEMBL15331531 | 0.81 | BRD4 (0.35) | PTGESALOX5 | |
| SCHEMBL15333163 | 0.81 | ALOX5 (0.38) | PTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |