Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | GRM8 | O00222 | 1/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nimorazole SCHEMBL2549842 | 0.90 | GLA (0.46) | GLAKMT2AMEN1ALDH1A1MAPT | |
| Nimorazole SCHEMBL2552501 | 0.88 | GLA (0.43) | GLACYP1A2KMT2AMEN1ALDH1A1 | |
| Nimorazole SCHEMBL2557042 | 0.85 | ALDH1A1 (0.39) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| Nimorazole SCHEMBL21836 | 0.84 | KMT2A (0.45) | CYP1A2KMT2AMEN1ALDH1A1MAPT | |
| Nimorazole SCHEMBL2555788 | 0.83 | POLB (0.44) | CYP1A2KMT2AMEN1ALDH1A1MAPT | |
| Nimorazole SCHEMBL2558233 | 0.82 | KMT2A (0.38) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| Nimorazole SCHEMBL2555549 | 0.82 | KMT2A (0.38) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| Nimorazole SCHEMBL2555550 | 0.82 | KMT2A (0.38) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| Nimorazole SCHEMBL2552669 | 0.81 | MEN1 (0.40) | CYP1A2KMT2AMEN1ALDH1A1MAPT | |
| Nimorazole SCHEMBL2556141 | 0.81 | PKM (0.43) | CYP1A2KMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130096123-A1 | RADIATION SENSITISER COMPOSITIONS | EUPHARMA PTY LTD (AU) | 2013-04-18 | — | — | US | claimed |
| EP-2558090-A1 | RADIATION SENSITISER COMPOSITIONS | Eupharma Pty Ltd (AU) | 2013-02-20 | — | — | EP | claimed |
| CN-102933213-A | Radiation sensitiser compositions | EUPHARMA PTY LTD | 2013-02-13 | — | — | CN | claimed |
| WO-2011127537-A1 | RADIATION SENSITISER COMPOSITIONS | PHEBRA PTY LTD (AU) | 2011-10-20 | — | — | WO | claimed |