Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 6/20 | 0.42 |
| ▸ | PPARA | Q07869 | 6/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2560281 | 0.87 | LDHA (0.65) | LDHAMTNR1AMTNR1BGAACYP1A2 | |
| SCHEMBL1475915 | 0.84 | LDHA (0.53) | LDHAMTNR1AMTNR1BCYP1A2PPARG | |
| SCHEMBL9331782 | 0.84 | LDHA (0.48) | LDHAMTNR1AMTNR1BGAACYP1A2 | |
| SCHEMBL10966266 | 0.84 | MTNR1A (0.45) | LDHAMTNR1AMTNR1BGAACYP1A2 | |
| SCHEMBL5411510 | 0.84 | MTNR1A (0.45) | LDHAMTNR1AMTNR1BGAACYP1A2 | |
| SCHEMBL8395078 | 0.83 | LMNA (0.51) | MTNR1AMTNR1BKMT2AMEN1LMNA | |
| SCHEMBL9774578 | 0.82 | LDHA (0.52) | LDHACYP1A2CYP2C19PPARGPPARA | |
| SCHEMBL10880781 | 0.80 | KMT2A (0.55) | LDHAMTNR1AMTNR1BGAACYP1A2 | |
| SCHEMBL855858 | 0.80 | ALDH1A1 (0.54) | MTNR1AMTNR1BPPARGPPARAKMT2A | |
| SCHEMBL6380944 | 0.79 | LDHA (0.62) | LDHAGAACYP1A2CYP2C9PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367680-B2 | Antibacterial small molecules and methods for their synthesis | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-02-05 | — | — | US | disclosed |
| US-20090270423-A1 | ANTIBACTERIAL SMALL MOLECULES AND METHODS FOR THEIR SYNTHESIS | NATIONAL SCIENCE FOUNDATION | 2009-10-29 | — | — | US | disclosed |
| EP-0344982-B1 | Alpha-adrenergic receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1994-11-23 | — | — | EP | disclosed |
| EP-0384676-B1 | Alpha-adrenergic receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1993-11-10 | — | — | EP | disclosed |
| EP-0384676-A1 | Alpha-adrenergic receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1990-08-29 | — | — | EP | disclosed |
| WO-1989012051-A1 | alpha-ADRENERGIC RECEPTOR ANTAGONISTS | SMITHKLINE BECKMAN CORPORATION (US) | 1989-12-14 | — | — | WO | disclosed |
| WO-1989012050-A1 | alpha-ADRENERGIC RECEPTOR ANTAGONISTS | SMITHKLINE BECKMAN CORPORATION (US) | 1989-12-14 | — | — | WO | disclosed |
| EP-0344980-A2 | Alpha-adrenergic receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1989-12-06 | — | — | EP | disclosed |
| EP-0344982-A2 | Alpha-adrenergic receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1989-12-06 | — | — | EP | disclosed |
| US-4508541-A | DETERGENTS | TEXACO INC. (US) | 1985-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270423-A1 | ANTIBACTERIAL SMALL MOLECULES AND METHODS FOR THEIR SYNTHESIS | CLSPN, FDPS, DHPS | LDHA 2853/4885MTNR1A 4513/4885MTNR1B 4243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.