Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.59 |
| ▸ | ACACB | O00763 | 1/20 | 0.54 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
| ▸ | PLK4 | O00444 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | PAK4 | O96013 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | PRKCG | P05129 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11200681 | 0.91 | L3MBTL1 (0.76) | L3MBTL1HRH3ACACBGRIA2CYP1A2 | |
| SCHEMBL10399987 | 0.84 | L3MBTL1 (0.67) | L3MBTL1HRH3ACACBGRIA2CYP1A2 | |
| SCHEMBL19717008 | 0.84 | L3MBTL1 (0.67) | L3MBTL1HRH3ACACBGRIA2CYP1A2 | |
| SCHEMBL15242991 | 0.83 | L3MBTL1 (0.45) | L3MBTL1HRH3KMT2AACHE | |
| SCHEMBL632892 | 0.82 | L3MBTL1 (0.65) | L3MBTL1HRH3ACACBGRIA2CYP1A2 | |
| SCHEMBL6824717 | 0.82 | L3MBTL1 (0.65) | L3MBTL1HRH3ACACBGRIA2CYP1A2 | |
| SCHEMBL13853398 | 0.82 | L3MBTL1 (0.65) | L3MBTL1HRH3ACACBGRIA2CYP1A2 | |
| SCHEMBL5578262 | 0.82 | L3MBTL1 (0.65) | L3MBTL1HRH3ACACBGRIA2CYP1A2 | |
| SCHEMBL13215733 | 0.82 | L3MBTL1 (0.65) | L3MBTL1HRH3ACACBGRIA2CYP1A2 | |
| SCHEMBL3903106 | 0.82 | L3MBTL1 (0.65) | L3MBTL1HRH3ACACBGRIA2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3580213-B1 | AMPA RECEPTOR POTENTIATORS | UNIV COLLEGE CARDIFF CONSULTANTS LTD (GB) | 2024-03-27 | — | — | EP | disclosed |
| CN-110520418-B | AMPA receptor potentiators | 加的夫大学学院咨询有限公司 | 2022-08-16 | — | — | CN | disclosed |
| US-11186567-B2 | AMPA receptor potentiators | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2021-11-30 | — | — | US | disclosed |
| US-11186567-B2 | AMPA receptor potentiators | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2021-11-30 | — | — | US | disclosed |
| US-20210139463-A1 | AMPA RECEPTOR POTENTIATORS | DRAIG THERAPEUTICS LTD (GB) | 2021-05-13 | — | — | US | disclosed |
| US-20210139463-A1 | AMPA RECEPTOR POTENTIATORS | DRAIG THERAPEUTICS LTD (GB) | 2021-05-13 | — | — | US | disclosed |
| CN-110520418-A | Ampa receptor reinforcing agent | UNIV SUSSEX | 2019-11-29 | — | — | CN | disclosed |
| WO-2018146486-A1 | AMPA RECEPTOR POTENTIATORS | THE UNIVERSITY OF SUSSEX (GB) | 2018-08-16 | — | — | WO | disclosed |
| EP-2611771-B1 | SUBSTITUTED HETEROARYL- AND ARYLALKYNYL BENZENE DERIVATIVES AS ACC-INHIBITORS FOR THE TREATMENT OF METABOLIC DISEASES | BOEHRINGER INGELHEIM INT (DE) | 2016-11-23 | — | — | EP | disclosed |
| EP-2611771-B1 | SUBSTITUTED HETEROARYL- AND ARYLALKYNYL BENZENE DERIVATIVES AS ACC-INHIBITORS FOR THE TREATMENT OF METABOLIC DISEASES | BOEHRINGER INGELHEIM INT (DE) | 2016-11-23 | — | — | EP | disclosed |
| WO-2008148832-A1 | COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEROF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |
| WO-2008148836-A1 | COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |
| EP-1996555-A1 | COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-12-03 | — | — | EP | disclosed |
| WO-2008053031-A1 | COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-05-08 | — | — | WO | disclosed |
| WO-2008053031-A1 | COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-05-08 | — | — | WO | disclosed |
| US-20080045532-A1 | Compounds which potentiate AMPA receptor and uses thereof in medicine | GLAXO GROUP LIMITED (GB) | 2008-02-21 | — | — | US | disclosed |
| US-20080045532-A1 | Compounds which potentiate AMPA receptor and uses thereof in medicine | GLAXO GROUP LIMITED (GB) | 2008-02-21 | — | — | US | disclosed |
| US-20080045532-A1 | Compounds which potentiate AMPA receptor and uses thereof in medicine | GLAXO GROUP LIMITED (GB) | 2008-02-21 | — | — | US | disclosed |
| WO-2007107539-A1 | COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2007-09-27 | — | — | WO | disclosed |
| WO-2007107539-A1 | COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2007-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139463-A1 | AMPA RECEPTOR POTENTIATORS | GRIN1, GRM1, GRM2 | L3MBTL1 3921/4885HRH3 342/4885ACACB 3910/4885 |
| US-11186567-B2 | AMPA receptor potentiators | GRIN1, GRM1, GRM2 | L3MBTL1 3921/4885HRH3 342/4885ACACB 3910/4885 |
| US-20080045532-A1 | Compounds which potentiate AMPA receptor and uses thereof in medicine | GRIN1, GRM2, GRM1 | L3MBTL1 4582/4885HRH3 775/4885ACACB 2073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.