SCHEMBL6824717

SCHEMBL6824717

O=C1CCCN1Cc1ccc(Br)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.65
HRH3 Q9Y5N1 1/20 0.59
ACACB O00763 1/20 0.54
KMT2A Q03164 2/20 0.49
POLB P06746 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
GRIA2 P42262 1/20 0.47
TNIK Q9UKE5 1/20 0.45
KCNH2 Q12809 1/20 0.45
CDC7 O00311 1/20 0.45
PLK4 O00444 1/20 0.45
AURKA O14965 1/20 0.45
MAPK13 O15264 1/20 0.45
PDPK1 O15530 1/20 0.45
DYRK3 O43781 1/20 0.45
PRKD3 O94806 1/20 0.45
MAP4K4 O95819 1/20 0.45
PAK4 O96013 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16891466 0.96 L3MBTL1 (0.70) L3MBTL1HRH3ACACBKMT2APOLB
SCHEMBL11200681 0.91 L3MBTL1 (0.76) L3MBTL1HRH3ACACBKMT2ACYP1A2
SCHEMBL19717008 0.84 L3MBTL1 (0.67) L3MBTL1HRH3ACACBKMT2ACYP1A2
SCHEMBL10399987 0.84 L3MBTL1 (0.67) L3MBTL1HRH3ACACBKMT2ACYP1A2
SCHEMBL3140840 0.83 KMT2A (0.53) L3MBTL1HRH3KMT2APOLBTDP1
SCHEMBL5578262 0.82 L3MBTL1 (0.65) L3MBTL1HRH3ACACBKMT2APOLB
SCHEMBL632892 0.82 L3MBTL1 (0.65) L3MBTL1HRH3ACACBKMT2ACYP1A2
SCHEMBL256037 0.82 L3MBTL1 (0.65) L3MBTL1HRH3ACACBKMT2ACYP1A2
SCHEMBL3903106 0.82 L3MBTL1 (0.65) L3MBTL1HRH3ACACBKMT2ACYP1A2
SCHEMBL13215733 0.82 L3MBTL1 (0.65) L3MBTL1HRH3ACACBKMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010905-A Pyrazolyl derivatives as anticancer agents 诺华股份有限公司 2026-05-12 CN disclosed
EP-4344702-B1 PYRAZOLYL DERIVATIVES USEFUL AS ANTI-CANCER AGENTS NOVARTIS AG (CH) 2026-01-28 EP disclosed
EP-4663630-A1 NOVEL BENZIMIDAZOLONE DERIVATIVE COMPOUND AS AUTOTAXIN INHIBITOR LG Chem, Ltd. (KR) 2025-12-17 EP disclosed
US-20250375432-A1 COMPOUNDS THAT MODULATES AMPA RECEPTOR FUNCTION UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2025-12-11 US disclosed
US-12479816-B2 20-HETE formation inhibitors University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2025-11-25 US disclosed
EP-4648853-A1 TARGETED DEGRADATION OF VAV1 Monte Rosa Therapeutics AG (CH) 2025-11-19 EP disclosed
US-12454525-B2 IL4I1 inhibitors and methods of use MERCK SHARP & DOHME LLC (US) 2025-10-28 US disclosed
US-12383540-B2 Compounds that modulates AMPA receptor function UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2025-08-12 US disclosed
US-20250205219-A1 TARGETED DEGRADATION OF VAV1 MONTE ROSA THERAPEUTICS AG (CH) 2025-06-26 US disclosed
US-12257247-B2 Targeted degradation of VAV1 MONTE ROSA THERAPEUTICS AG (CH) 2025-03-25 US disclosed
EP-3386950-A1 SUBSTITUTED BENZAZINONES AS ANTIBACTERIAL COMPOUNDS GlaxoSmithKline Intellectual Property Development Limited (GB) 2018-10-17 EP disclosed
CN-108368053-A Substituted benzazepine derivatives as antibacterial compounds 葛兰素史密斯克莱知识产权发展有限公司 2018-08-03 CN disclosed
WO-2017098440-A1 SUBSTITUTED BENZAZINONES AS ANTIBACTERIAL COMPOUNDS GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2017-06-15 WO disclosed
CN-104507940-B Heterocyclic compounds 武田药品工业株式会社 2017-01-25 CN disclosed
US-20160251352-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICALS CO (JP) 2016-09-01 US disclosed
US-9371320-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-06-21 US disclosed
US-20150141406-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-05-21 US disclosed
EP-2857400-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2015-04-08 EP disclosed
CN-104507940-A Heterocyclic compounds TAKEDA PHARMACEUTICAL 2015-04-08 CN disclosed
WO-2004046137-A1 NEW TRICYCLIC ANGIOTENSIN II AGONISTS VICORE PHARMA AB (SE) 2004-06-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250375432-A1 COMPOUNDS THAT MODULATES AMPA RECEPTOR FUNCTION GRIN1, GRM1, GRIN2A L3MBTL1 3079/4885HRH3 285/4885ACACB 1926/4885
US-20160251352-A1 HETEROCYCLIC COMPOUND JAK2, JAK1, STAT3 L3MBTL1 2322/4885HRH3 3535/4885ACACB 3794/4885
US-12383540-B2 Compounds that modulates AMPA receptor function GRIN1, GRM1, GRIN2A L3MBTL1 3006/4885HRH3 297/4885ACACB 2119/4885
US-12257247-B2 Targeted degradation of VAV1 VAV1, KRAS, CBL L3MBTL1 1667/4885HRH3 2417/4885ACACB 4377/4885
US-12479816-B2 20-HETE formation inhibitors CYP4A22, ALOX5, ALOX15 L3MBTL1 4595/4885HRH3 2749/4885ACACB 506/4885
US-20150141406-A1 HETEROCYCLIC COMPOUND JAK2, JAK1, STAT3 L3MBTL1 2322/4885HRH3 3535/4885ACACB 3794/4885
US-12454525-B2 IL4I1 inhibitors and methods of use IL4I1, IL4, IL2 L3MBTL1 4116/4885HRH3 776/4885ACACB 3349/4885
US-20250205219-A1 TARGETED DEGRADATION OF VAV1 VAV1, KRAS, CBL L3MBTL1 1667/4885HRH3 2417/4885ACACB 4377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.