SCHEMBL2560385

SCHEMBL2560385

Oc1ccc2c(c1)Oc1ccc(O)cc1S2.Oc1ccc2c(c1)Sc1cccc(O)c1S2

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.47
TYR P14679 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29368510 0.85 ALOX5 (0.60) ALOX5TYRALDH1A1LMNA
SCHEMBL124605 0.85 ALOX5 (0.60) ALOX5TYRALDH1A1LMNA
SCHEMBL7803344 0.85 ALOX5 (0.43) ALOX5TYR
SCHEMBL29431895 0.82 CYP3A4 (0.41) ALOX5TYRALDH1A1LMNA
SCHEMBL167395 0.82 CYP3A4 (0.41) ALOX5TYRALDH1A1LMNA
SCHEMBL8207934 0.77 TRPA1 (0.45) ALOX5TYRALDH1A1LMNA
SCHEMBL2197852 0.72 ALOX5 (0.56) ALOX5ALDH1A1LMNA
SCHEMBL30936097 0.72 ALOX5 (0.56) ALOX5ALDH1A1LMNA
SCHEMBL1309739 0.71 ALOX5 (0.38) ALOX5ALDH1A1LMNA
SCHEMBL31084126 0.70 ALOX5 (0.55) ALOX5ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2561004-A1 POLYCARBONATE COPOLYMER Styron Europe GmbH (CH) 2013-02-27 EP disclosed
US-20110288243-A1 Carbonate Block Copolymers JUEPTNER GUENTER A (DE) 2011-11-24 US disclosed
WO-2011131366-A1 POLYCARBONATE COPOLYMER STYRON EUROPE GMBH (CH) 2011-10-27 WO disclosed