Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR39 | O43194 | 2/20 | 0.41 |
| ▸ | PIK3C3 | Q8NEB9 | 4/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | CDK4 | P11802 | 2/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.36 |
| ▸ | CCND1 | P24385 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | PAK4 | O96013 | 1/20 | 0.36 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25607003 | 0.79 | GPR39 (0.56) | GPR39PIK3C3HRH4CDK1CDK4 | |
| SCHEMBL27109893 | 0.78 | GPR39 (0.58) | GPR39PIK3C3HRH4CDK1CDK4 | |
| SCHEMBL19477097 | 0.75 | HRH3 (0.56) | GPR39HRH4CDK1CDK4CCNB1 | |
| SCHEMBL19477384 | 0.73 | PAK4 (0.49) | GPR39PIK3C3HRH4CDK1CDK4 | |
| SCHEMBL19477350 | 0.73 | PAK4 (0.49) | GPR39PIK3C3HRH4CDK1CDK4 | |
| SCHEMBL19477096 | 0.71 | BRD4 (0.47) | HRH4CDK2 | |
| SCHEMBL10065608 | 0.69 | CYP1A2 (0.47) | CDK1CDK2 | |
| SCHEMBL6458263 | 0.69 | JAK1 (0.43) | HRH4CDK2MAPK8MERTK | |
| SCHEMBL6458275 | 0.69 | JAK1 (0.43) | HRH4CDK2MAPK8MERTK | |
| Hydrochloric Acid SCHEMBL6923547 | 0.66 | MEN1 (0.49) | CDK2MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442947-B1 | AMINE-SUBSTITUTED ARYL OR HETEROARYL COMPOUNDS AS EHMT1 AND EHMT2 INHIBITORS | EPIZYME INC (US) | 2023-06-07 | — | — | EP | disclosed |