SCHEMBL2560745

SCHEMBL2560745

CC(=O)CC(=O)Nc1ccc(C(=O)O)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.66
CA2 P00918 3/20 0.57
CA1 P00915 2/20 0.57
CA4 P22748 1/20 0.57
CA7 P43166 1/20 0.57
POLB P06746 2/20 0.56
TSHR P16473 1/20 0.56
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
CYP1A2 P05177 2/20 0.54
CYP2C9 P11712 1/20 0.54
ALDH1A1 P00352 5/20 0.53
KDM4E B2RXH2 1/20 0.53
CYP2C19 P33261 1/20 0.53
HIF1A Q16665 1/20 0.53
CA12 O43570 2/20 0.53
CA9 Q16790 2/20 0.53
HPGD P15428 1/20 0.50
RAB9A P51151 1/20 0.50
STAT3 P40763 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL593172 0.88 MAPT (0.74) MAPTCA2CA1CA4CA7
SCHEMBL31570085 0.86 MAPT (0.64) MAPTCA2CA1CA4CA7
SCHEMBL2843886 0.84 CA12 (0.56) CA2CA1POLBTSHRMEN1
SCHEMBL7821936 0.83 KMT2A (0.58) CA2CA1POLBMEN1KMT2A
SCHEMBL2568204 0.83 CA1 (0.60) MAPTCA2CA1CA4CA7
SCHEMBL19024618 0.83 MAPT (0.59) MAPTCA2CA1CA4CA7
SCHEMBL1663647 0.82 CA2 (0.58) CA2CA1POLBTSHRMEN1
SCHEMBL1395934 0.82 ALDH1A1 (0.71) MAPTCA2CA1POLBMEN1
SCHEMBL11052703 0.82 MAPT (0.73) MAPTPOLBMEN1KMT2ACYP1A2
SCHEMBL6204592 0.82 MAPT (0.67) MAPTCA2CA1CA4CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0263951-B1 Disazo compounds and compositions containing them BASF LACKE & FARBEN (DE) 1994-06-15 EP claimed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
EP-3540059-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2019-09-18 EP disclosed
EP-2558577-B1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION AS (DK) 2018-12-12 EP disclosed
US-20130281324-A1 BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2013-10-24 US disclosed
EP-2558577-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2013-02-20 EP disclosed
WO-2011127933-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2011-10-20 WO disclosed
US-8022117-B2 Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2011-09-20 US disclosed
US-8022117-B2 Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2011-09-20 US disclosed
EP-0076024-B1 FLUIDISING AGENT IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-09-18 EP disclosed
US-4474609-A Recrystallization-resistant monoazo pigment mixtures of high tinctorial strength, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1984-10-02 US disclosed
US-4461647-A NONAQUEOUS DISPERSION OF PIGMENTS AND DISAZO FLOW CONTROL AGENT IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1984-07-24 US disclosed
EP-0076024-A1 Fluidising agent IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-04-06 EP disclosed
EP-0012944-B1 COLOUR-FAST MONOAZO PIGMENT MIXTURES STABLE AGAINST RECRYSTALLISATION, PROCESS FOR THEIR PREPARATION AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1982-06-23 EP disclosed
US-4334932-A Pigment formulations, processes for their preparation and their use for pigmenting aqueous, alcoholic or aqueous-alcoholic printing ink systems and colored lacquer systems CIBA-GEIGY CORPORATION (US) 1982-06-15 US disclosed
EP-0039307-A2 Pigment preparations,process for preparing them and their use in pigmenting aqueous, alcoholic or aqueous-alcoholic ink and paint systems CIBA-GEIGY AG (CH) 1981-11-04 EP disclosed
US-4221709-A Azo pigments DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 1980-09-09 US disclosed
EP-0012944-A1 Colour-fast monoazo pigment mixtures stable against recrystallisation, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1980-07-09 EP disclosed
US-4118384-A DIAZOTIZATION BAYER AKTIENGESELLSCHAFT (DE) 1978-10-03 US disclosed