SCHEMBL25607474

SCHEMBL25607474

CNCCCNCCCCN(C)CCCNC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.40
CYP2C19 P33261 3/20 0.39
CYP1A2 P05177 1/20 0.39
PRMT3 O60678 1/20 0.39
CARM1 Q86X55 1/20 0.39
PRMT6 Q96LA8 1/20 0.39
PRMT1 Q99873 1/20 0.39
PRMT8 Q9NR22 1/20 0.39
PAOX Q6QHF9 3/20 0.37
EPHX1 P07099 1/20 0.37
CHRM2 P08172 3/20 0.37
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
MEN1 O00255 1/20 0.35
GLA P06280 1/20 0.35
KMT2A Q03164 1/20 0.35
S1PR2 O95136 1/20 0.34
S1PR1 P21453 1/20 0.34
S1PR3 Q99500 1/20 0.34
S1PR5 Q9H228 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13327383 0.91 TDP1 (0.40) TDP1CYP2C19CYP1A2PRMT3CARM1
SCHEMBL19546063 0.91 PRMT3 (0.46) TDP1PRMT3CARM1PRMT6PRMT1
SCHEMBL14178222 0.88 EPHX1 (0.48) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL25075475 0.88 PRMT3 (0.48) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL16317337 0.88 PRMT3 (0.48) TDP1PRMT3CARM1PRMT6PRMT1
SCHEMBL22946807 0.85 EPHX1 (0.50) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL1229873 0.85 EPHX1 (0.50) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL13540767 0.85 PRMT3 (0.46) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL1231390 0.85 PRMT3 (0.50) TDP1CYP2C19PRMT3CARM1PRMT6
SCHEMBL27368885 0.83 PRMT1 (0.50) PRMT3CARM1PRMT6PRMT1PRMT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230181742-A1 AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME Life Technologies Corporation 2023-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230181742-A1 AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME SNRPA, NUDT21, SOAT2 TDP1 1314/4885CYP2C19 4605/4885CYP1A2 4635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.