Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL256086 | 0.82 | KCNH2 (0.44) | GRM5PRSS1PRSS2PRSS3PTGDR2 | |
| SCHEMBL8350133 | 0.80 | PTGDR2 (0.35) | GRM5PRSS1PRSS2PRSS3PTGDR2 | |
| SCHEMBL9967683 | 0.75 | GRM5 (0.39) | GRM5PRSS1PRSS2PRSS3PTGDR2 | |
| SCHEMBL2109413 | 0.75 | GRM5 (0.39) | GRM5PRSS1PRSS2PRSS3PTGDR2 | |
| SCHEMBL6810736 | 0.72 | ALDH1A1 (0.48) | GRM5PRSS1PRSS2PRSS3PTGDR2 | |
| SCHEMBL29251289 | 0.72 | GRM5 (0.52) | GRM5PTGDR2TRPV3 | |
| SCHEMBL2109417 | 0.71 | ALDH1A1 (0.37) | GRM5PRSS1PRSS2PRSS3PTGDR2 | |
| SCHEMBL8278416 | 0.70 | PRSS1 (0.45) | GRM5PRSS1PRSS2PRSS3PTGDR2 | |
| Charcoal, Activated SCHEMBL31286314 | 0.70 | GRM5 (0.50) | GRM5PTGDR2TRPV3 | |
| Fluoride SCHEMBL31286347 | 0.70 | GRM5 (0.50) | GRM5PTGDR2TRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012028578-A1 | SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | WO | disclosed |