Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25218498 | 0.79 | — | — | |
| SCHEMBL17986818 | 0.72 | ADORA3 (0.34) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16427770 | 0.69 | FLT3 (0.45) | — | |
| SCHEMBL25420577 | 0.68 | CYP11B2 (0.42) | KDM4E | |
| SCHEMBL25417901 | 0.66 | ALDH1A1 (0.33) | — | |
| SCHEMBL25346341 | 0.66 | ADORA3 (0.34) | DAO | |
| SCHEMBL21353952 | 0.62 | CYP1A2 (0.35) | — | |
| SCHEMBL16631782 | 0.59 | — | — | |
| SCHEMBL24231341 | 0.58 | MAPT (0.34) | — | |
| SCHEMBL24375561 | 0.58 | CYP1A2 (0.31) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107714-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |