Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 5/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2995196 | 0.96 | FADS1 (0.33) | FADS1LIPEKCNH2HRH3PIK3CD | |
| SCHEMBL2565212 | 0.93 | FADS1 (0.35) | FADS1LIPEKCNH2HRH3PIK3CD | |
| SCHEMBL2564954 | 0.88 | FADS1 (0.37) | FADS1LIPEKCNH2HRH3PIK3CD | |
| SCHEMBL13266554 | 0.85 | HRH3 (0.36) | FADS1LIPEKCNH2HRH3PIK3CD | |
| SCHEMBL2561951 | 0.84 | LIPE (0.40) | FADS1LIPEKCNH2HRH3PIK3CD | |
| SCHEMBL2564400 | 0.84 | FADS1 (0.35) | FADS1LIPEKCNH2HRH3PIK3CD | |
| SCHEMBL2564084 | 0.84 | FADS1 (0.35) | FADS1LIPEKCNH2HRH3PIK3CD | |
| SCHEMBL2568067 | 0.83 | FADS1 (0.37) | FADS1LIPEKCNH2HRH3PIK3CD | |
| SCHEMBL2564033 | 0.82 | FADS1 (0.35) | FADS1LIPEKCNH2HRH3PIK3CD | |
| SCHEMBL2567951 | 0.81 | ALDH1A1 (0.42) | FADS1LIPEKCNH2HRH3PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382218-A1 | DELTA-5-DESATURASE INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010087467-A1 | DELTA-5-DESATURASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-05 | — | — | WO | disclosed |