Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18220179 | 0.95 | LMNA (0.46) | ALDH1A1L3MBTL1KDM4EHPGDPOLB | |
| SCHEMBL24068152 | 0.90 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1KDM4EHPGDPOLB | |
| SCHEMBL18220185 | 0.89 | LMNA (0.47) | ALDH1A1L3MBTL1KDM4EHPGDPOLB | |
| SCHEMBL25610046 | 0.86 | SLC16A3 (0.33) | ALDH1A1L3MBTL1HPGDKMT2AMEN1 | |
| SCHEMBL18220194 | 0.85 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1KDM4EHPGDPOLB | |
| SCHEMBL18220212 | 0.85 | DNM1 (0.38) | ALDH1A1L3MBTL1KDM4ELMNAKMT2A | |
| SCHEMBL17120800 | 0.83 | DNM1 (0.37) | ALDH1A1L3MBTL1KDM4ELMNAKMT2A | |
| SCHEMBL18220181 | 0.82 | SLC16A3 (0.33) | ALDH1A1HPGDLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL17120860 | 0.82 | MEN1 (0.45) | ALDH1A1KDM4EPOLBLMNAKMT2A | |
| SCHEMBL25609229 | 0.82 | LMNA (0.49) | ALDH1A1L3MBTL1KDM4EHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119761-B1 | AMYLOID TARGETING AGENTS AND METHODS OF USING THE SAME | AMYDIS DIAGNOSTICS INC (US) | 2023-06-07 | — | — | EP | disclosed |