Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2569086 | 0.93 | FAAH (0.44) | FAAHTSHRSMN1; SMN2MAPT | |
| SCHEMBL6866925 | 0.81 | PHF8 (0.46) | SMN1; SMN2LMNAKDM4EKDM5CEGLN1 | |
| SCHEMBL10630200 | 0.80 | TSHR (0.43) | FAAHTSHRSMN1; SMN2MAPTKDM4E | |
| SCHEMBL10628189 | 0.80 | FAAH (0.46) | FAAHTSHRSMN1; SMN2MAPT | |
| Acetonitrile SCHEMBL28323144 | 0.78 | LMNA (0.46) | TSHRBBOX1HSD17B10MEN1KMT2A | |
| SCHEMBL10634427 | 0.78 | FAAH (0.50) | FAAHEPHX2TSHRSMN1; SMN2MEN1 | |
| SCHEMBL10631585 | 0.76 | MCL1 (0.46) | FAAHMAPT | |
| SCHEMBL2566414 | 0.74 | MAPT (0.54) | FAAHEPHX2TSHRHSD17B10MAPT | |
| Ethane SCHEMBL1291473 | 0.73 | — | — | |
| SCHEMBL20263715 | 0.73 | MCL1 (0.39) | FAAHTSHRSMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382218-A1 | DELTA-5-DESATURASE INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010087467-A1 | DELTA-5-DESATURASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-05 | — | — | WO | disclosed |