Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 6/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | KDM5C | P41229 | 4/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.46 |
| ▸ | KDM6B | O15054 | 2/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10631585 | 0.91 | MCL1 (0.46) | MCL1CTSLCTSS | |
| SCHEMBL10628189 | 0.81 | FAAH (0.46) | MCL1SMN1; SMN2 | |
| SCHEMBL29952905 | 0.81 | MCL1 (0.43) | MCL1CTSLCTSS | |
| SCHEMBL10630200 | 0.81 | TSHR (0.43) | KDM4EMCL1SMN1; SMN2CTSLCTSS | |
| SCHEMBL2561244 | 0.81 | FAAH (0.40) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL20263736 | 0.80 | MCL1 (0.41) | KDM4EMCL1CTSLCTSS | |
| SCHEMBL6442524 | 0.79 | CTSS (0.35) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL2442181 | 0.79 | PHF8 (0.48) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL10634427 | 0.79 | FAAH (0.50) | MCL1SMN1; SMN2 | |
| SCHEMBL15468338 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1452522-A2 | Novel compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2004-09-01 | — | — | EP | disclosed |