Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 5/20 | 0.36 |
| ▸ | ITK | Q08881 | 2/20 | 0.36 |
| ▸ | TGM2 | P21980 | 4/20 | 0.36 |
| ▸ | F13A1 | P00488 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TGM1 | P22735 | 1/20 | 0.34 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.34 |
| ▸ | GSTO1 | P78417 | 3/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.33 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31045687 | 0.74 | KDM4E (0.38) | LMNA | |
| SCHEMBL17803639 | 0.72 | CA12 (0.37) | LMNA | |
| SCHEMBL2552963 | 0.70 | CYP3A4 (0.57) | LMNA | |
| SCHEMBL10579911 | 0.70 | AURKA (0.33) | — | |
| SCHEMBL3823196 | 0.68 | DPYD (0.42) | — | |
| SCHEMBL2030553 | 0.67 | TSHR (0.32) | — | |
| SCHEMBL542555 | 0.66 | — | — | |
| SCHEMBL65897 | 0.65 | — | — | |
| SCHEMBL4359910 | 0.65 | KDM4E (0.40) | — | |
| SCHEMBL7209768 | 0.65 | IKBKB (0.41) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011128374-A1 | INSULIN-SIRNA CONJUGATES | SANOFI (FR) | 2011-10-20 | — | — | WO | claimed |
| WO-2011128374-A1 | INSULIN-SIRNA CONJUGATES | SANOFI (FR) | 2011-10-20 | — | — | WO | disclosed |