SCHEMBL65897

SCHEMBL65897

Nc1nc(=O)[nH]cc1O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5143009 0.76
SCHEMBL4512381 0.76
Flucytosine SCHEMBL8160959 0.73 ALDH1A1 (0.37)
SCHEMBL1765946 0.73
SCHEMBL65486 0.73
Flucytosine SCHEMBL24063 0.73
SCHEMBL30609151 0.73
SCHEMBL1231792 0.73 ATAD2 (0.37)
SCHEMBL22008 0.73
SCHEMBL27533747 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3234 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
US-12630851-B2 Polynucleotide modification methods OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-05-19 US claimed
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 CN claimed
US-20260098287-A1 METHOD AND KIT FOR REGENERATING REUSABLE INITIATORS FOR NUCLEIC ACID SYNTHESIS CHENG-YAO CHEN (TW) 2026-04-09 US claimed
EP-4665856-A2 DNA COMPOSITIONS COMPRISING MODIFIED CYTOSINE Flagship Pioneering Innovations VII, LLC (US) 2025-12-24 EP claimed
EP-4638717-A2 ENGINEERED RNA LIGASE VARIANTS Codexis, Inc. (US) 2025-10-29 EP claimed
CN-120142648-A Small molecule immunodetection kit and small molecule immunodetection method 中国农业科学院蔬菜花卉研究所 2025-06-13 CN claimed
WO-2025111452-A2 CHEMICAL MODIFICATIONS IN PEgRNA and ngRNAs PRIME MEDICINE, INC. (US) 2025-05-30 WO claimed
EP-1322656-A2 MODULATION OF IMMUNOSTIMULATORY ACTIVITY OF IMMUNOSTIMULATORY OLIGONUCLEOTIDE ANALOGS BY POSITIONAL CHEMICAL CHANGES HYBRIDON, INC. (US) 2003-07-02 EP claimed
WO-2003035836-A2 MODULATION OF IMMUNOSTIMULATORY PROPERTIES OF OLIGONUCLEOTIDE-BASED COMPOUNDS BY OPTIMAL PRESENTATION OF 5' ENDS HYBRIDON INC. (US) 2003-05-01 WO claimed
EP-1281757-A1 Method for the production of nucleic acids consisting of stochastically combined parts of source nucleic acids Direvo Biotech AG (DE) 2003-02-05 EP claimed
US-20020137714-A1 Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes IDERA PHARMACEUTICALS, INC 2002-09-26 US claimed
WO-2002026757-A2 MODULATION OF IMMUNOSTIMULATORY ACTIVITY OF IMMUNOSTIMULATORY OLIGONUCLEOTIDE ANALOGS BY POSITIONAL CHEMICAL CHANGES HYBRIDON, INC. (US) 2002-04-04 WO claimed
EP-0706581-A4 DNA PROFILES AS AN INDICATOR OF CELLULAR REDOX POTENTIAL AND CANCER RISK PACIFIC NORTHWEST RESEARCH FOU (US) 1999-02-10 EP claimed
US-5665553-A Methods for determining and modulating cellular redox potential and genotoxic states PACIFIC NORTHWEST RESEARCH FOUNDATION (US) 1997-09-09 US claimed
US-5601981-A ASSAYING DNA FROM TEST SPECIMEN FOR CONCENTRATION OF RING-OPENED AND HYDROXYL DERIVATIVES, COMPARING, WHEREIN REDUCTIVE CELLULAR REDOX POTENTIAL EXISTS WHEN FORMATION OF RING-OPENED OVER HYDROXYL DERIVATIVES IS FAVORED PACIFIC NORTHWEST RESEARCH FOUNDATION (US) 1997-02-11 US claimed
EP-0706581-A1 DNA PROFILES AS AN INDICATOR OF CELLULAR REDOX POTENTIAL AND CANCER RISK PACIFIC NORTHWEST RESEARCH FOUNDATION (US) 1996-04-17 EP claimed
WO-1994025626-A1 DNA PROFILES AS AN INDICATOR OF CELLULAR REDOX POTENTIAL AND CANCER RISK PACIFIC NORTHWEST RESEARCH FOUNDATION (US) 1994-11-10 WO claimed