SCHEMBL7209768

SCHEMBL7209768

NC(=O)c1c[nH]c(=O)nc1N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IKBKB O14920 1/20 0.41
ALDH1A1 P00352 3/20 0.39
ATM Q13315 1/20 0.39
GDA Q9Y2T3 1/20 0.38
KDM4E B2RXH2 1/20 0.37
GLA P06280 1/20 0.37
GAA P10253 1/20 0.37
HPGD P15428 1/20 0.37
EEF2K O00418 2/20 0.36
PDPK1 O15530 2/20 0.34
RCE1 Q9Y256 1/20 0.34
CSNK1A1 P48729 2/20 0.33
DYRK1B Q9Y463 2/20 0.33
PLK4 O00444 1/20 0.33
CHEK1 O14757 1/20 0.33
AURKA O14965 1/20 0.33
DAPK3 O43293 1/20 0.33
MAP4K4 O95819 1/20 0.33
CSF1R P07333 1/20 0.33
RET P07949 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4359910 0.84 KDM4E (0.40) ALDH1A1KDM4ECLK4PIM3TSHR
SCHEMBL28361145 0.82 PBRM1 (0.38) ALDH1A1KDM4EHPGDTSHRMEN1
SCHEMBL932304 0.77
SCHEMBL532660 0.77
SCHEMBL3817207 0.77
SCHEMBL10580660 0.75 MAPT (0.47) ALDH1A1GLAGAACDK5BTK
Flucytosine SCHEMBL27602120 0.73 TSHR (0.33) ALDH1A1GDATSHRMAPT
SCHEMBL21223630 0.73 KDM3B (0.33) KDM4ECLK4PIM3TSHR
SCHEMBL65897 0.72
SCHEMBL28207476 0.72 GABRA1 (0.44) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4739992-A1 DETECTION OF TARGET MOLECULES IN DRIED BIOLOGIC MATRICES SomaLogic Operating Co., Inc. (US) 2026-05-13 EP disclosed
WO-2025010324-A1 DETECTION OF TARGET MOLECULES IN DRIED BIOLOGIC MATRICES SOMALOGIC OPERATING CO., INC. (US) 2025-01-09 WO disclosed
CN-112638845-B Improved proteomic multiplex assays 私募蛋白质体运营有限公司 2024-07-30 CN disclosed
EP-1284741-A2 3'-OR 2'-HYDROXYMETHYL SUBSTITUTED NUCLEOSIDE DERIVATIVES FOR TREATMENT OF HEPATITIS VIRUS INFECTIONS Pharmasset, Ltd. (BB) 2003-02-26 EP disclosed
WO-2001079246-A2 3'-OR 2'-HYDROXYMETHYL SUBSTITUTED NUCLEOSIDE DERIVATIVES FOR TREATMENT OF HEPATITIS VIRUS INFECTIONS PHARMASSET, LTD. (BB) 2001-10-25 WO disclosed