⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25612969 | 0.73 | — | — | |
| SCHEMBL25612958 | 0.69 | POLB (0.34) | — | |
| SCHEMBL25612973 | 0.69 | MAPT (0.35) | — | |
| SCHEMBL25613239 | 0.67 | CASP1 (0.32) | — | |
| SCHEMBL25612974 | 0.59 | MAPT (0.35) | — | |
| SCHEMBL12299456 | 0.59 | MBOAT4 (0.37) | — | |
| SCHEMBL16080761 | 0.58 | KDM4E (0.39) | — | |
| SCHEMBL13114352 | 0.58 | — | — | |
| SCHEMBL20416974 | 0.58 | CYP1A2 (0.33) | — | |
| SCHEMBL13459877 | 0.57 | CYP1A2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159527-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON BIOSCIENCES, LTD. (CN) | 2023-05-25 | — | — | US | disclosed |