⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15339537 | 0.77 | RAB9A (0.36) | — | |
| SCHEMBL20417234 | 0.74 | GRM5 (0.30) | — | |
| SCHEMBL25612974 | 0.73 | MAPT (0.35) | — | |
| SCHEMBL25612973 | 0.73 | MAPT (0.35) | — | |
| SCHEMBL25612971 | 0.73 | — | — | |
| SCHEMBL25612963 | 0.71 | KDM4E (0.33) | — | |
| SCHEMBL25613239 | 0.71 | CASP1 (0.32) | — | |
| SCHEMBL20417024 | 0.70 | NOTUM (0.31) | — | |
| SCHEMBL20417287 | 0.69 | — | — | |
| SCHEMBL12299456 | 0.67 | MBOAT4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159527-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON BIOSCIENCES, LTD. (CN) | 2023-05-25 | — | — | US | disclosed |