Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.34 |
| ▸ | OTUD7B | Q6GQQ9 | 3/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | APOBEC3B | Q9UH17 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25612826 | 0.78 | XDH (0.43) | CSNK2A2CSNK2A1KDM4EALDH1A1POLB | |
| SCHEMBL25613016 | 0.72 | MKNK1 (0.45) | — | |
| SCHEMBL25612824 | 0.67 | MAPT (0.42) | CSNK2A2CSNK2A1KDM4EALDH1A1POLB | |
| SCHEMBL25418143 | 0.62 | XDH (0.42) | CSNK2A2CSNK2A1SCDKDRPDE10A | |
| SCHEMBL25613441 | 0.61 | USP30 (0.41) | — | |
| SCHEMBL25605337 | 0.59 | MKNK1 (0.64) | CCNE1CDK2 | |
| SCHEMBL29277511 | 0.58 | CA1 (0.39) | — | |
| SCHEMBL17014697 | 0.58 | ALDH1A1 (0.48) | ALDH1A1KMT2A | |
| SCHEMBL5836105 | 0.57 | CDK2 (0.70) | CCNE1CDK2CDK5KDM4EALDH1A1 | |
| SCHEMBL24617492 | 0.57 | CYP11B1 (0.46) | CDK5KDM4EALDH1A1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107714-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |