Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | APOBEC3B | Q9UH17 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 6/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30481263 | 0.81 | CSNK2A2 (0.41) | MAPTKDM4EALDH1A1KMT2ARAB9A | |
| SCHEMBL25420455 | 0.81 | CSNK2A2 (0.41) | MAPTKDM4EALDH1A1KMT2ARAB9A | |
| SCHEMBL25612327 | 0.75 | MKNK1 (0.54) | ROCK2 | |
| SCHEMBL25612826 | 0.74 | XDH (0.43) | MAPTKDM4EALDH1A1POLBGFER | |
| SCHEMBL25613017 | 0.67 | CSNK2A2 (0.34) | MAPTKDM4EALDH1A1POLBGFER | |
| SCHEMBL16335425 | 0.61 | BTK (0.73) | — | |
| SCHEMBL7284132 | 0.61 | MLYCD (0.56) | MAPTKDM4EALDH1A1POLBGFER | |
| SCHEMBL25605163 | 0.60 | PDE10A (0.49) | MAPTKDM4EALDH1A1KMT2ARAB9A | |
| SCHEMBL29265898 | 0.58 | LRRK2 (0.33) | — | |
| SCHEMBL30326369 | 0.58 | LRRK2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107714-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |