SCHEMBL25613102

SCHEMBL25613102

CCN1CCC1COc1nc2[nH]ccc2cc1C(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ FEN1 P39748 1/20 0.31
▸ JAK1 P23458 1/20 0.30
▸ PIK3CD O00329 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25613112 0.94 TDP1 (0.35) —
SCHEMBL25613103 0.87 CHRNA3 (0.42) —
SCHEMBL24005764 0.85 PIK3CD (0.33) JAK1PIK3CD
SCHEMBL25613114 0.83 CHRNB4 (0.46) —
SCHEMBL25613101 0.82 JAK2 (0.34) JAK1
SCHEMBL25613092 0.79 CDK2 (0.40) —
SCHEMBL25613094 0.79 CDK2 (0.38) FEN1
SCHEMBL25613110 0.79 JAK2 (0.38) JAK1
SCHEMBL25613097 0.78 CHRNB4 (0.39) —
SCHEMBL25613109 0.78 P2RX3 (0.36) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159527-A1 COMPOUNDS AS BCL-2 INHIBITORS FOCHON BIOSCIENCES, LTD. (CN) 2023-05-25 — — US disclosed
US-20230159527-A1 COMPOUNDS AS BCL-2 INHIBITORS FOCHON BIOSCIENCES, LTD. (CN) 2023-05-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159527-A1 COMPOUNDS AS BCL-2 INHIBITORS BCL2, BCL2L2, BCL2L1 FEN1 1864/4885JAK1 3603/4885PIK3CD 965/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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