Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 4/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | CFB | P00751 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25613102 | 0.85 | FEN1 (0.31) | PIK3CDJAK1 | |
| SCHEMBL24005915 | 0.80 | CHRM3 (0.39) | CHEK1 | |
| SCHEMBL25613112 | 0.79 | TDP1 (0.35) | CHEK1 | |
| SCHEMBL24005745 | 0.76 | SLC6A4 (0.36) | SLC6A4CHEK1 | |
| SCHEMBL24005759 | 0.75 | FGFR1 (0.39) | PIK3CDFGFR1KDRPIK3CG | |
| SCHEMBL24005914 | 0.74 | CHRNB2 (0.47) | CHRNB4CHRNA3 | |
| SCHEMBL25613103 | 0.71 | CHRNA3 (0.42) | CHRNB4CHRNA3 | |
| SCHEMBL24005765 | 0.71 | LTA4H (0.48) | — | |
| SCHEMBL24005740 | 0.70 | JAK3 (0.41) | PIK3CDJAK1FGFR1KDRJAK3 | |
| SCHEMBL24005743 | 0.69 | CDK8 (0.40) | PIK3CDFGFR1KDRPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021223736-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2021-11-11 | — | — | WO | disclosed |