Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 9/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 9/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.43 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.43 |
| ▸ | AOC2 | O75106 | 2/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 5/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30835180 | 0.84 | HCAR2 (0.48) | CHRNB2CHRNA4AOC2MKNK1MKNK2 | |
| SCHEMBL1423044 | 0.84 | HCAR2 (0.48) | CHRNB2CHRNA4AOC2MKNK1MKNK2 | |
| SCHEMBL7826720 | 0.82 | SLC9A1 (0.39) | CHRNB2CHRNA4SIRT2SIRT1SIRT3 | |
| SCHEMBL2275659 | 0.82 | AOC2 (0.39) | CHRNB2CHRNA4SIRT2SIRT1SIRT3 | |
| SCHEMBL7825483 | 0.78 | ATM (0.56) | AOC2CYP11B1CYP11B2 | |
| SCHEMBL2841794 | 0.76 | SIRT2 (0.54) | CHRNB2CHRNA4SIRT2SIRT1SIRT3 | |
| SCHEMBL3108140 | 0.76 | AOC2 (0.69) | AOC2 | |
| SCHEMBL30811630 | 0.74 | CHRNB2 (0.76) | CHRNB2CHRNA4SIRT2SIRT1SIRT3 | |
| SCHEMBL30837593 | 0.74 | CHRNB2 (0.76) | CHRNB2CHRNA4SIRT2SIRT1SIRT3 | |
| SCHEMBL26428995 | 0.74 | CHRNB2 (0.76) | CHRNB2CHRNA4SIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104209-A1 | METTL3 INHIBITOR COMPOUND | 上海昂阔医药有限公司 | 2023-06-15 | — | — | WO | disclosed |