Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 14/20 | 0.54 |
| ▸ | CHRNA3 | P32297 | 14/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 13/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 13/20 | 0.54 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.39 |
| ▸ | CHRNG | P07510 | 1/20 | 0.39 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.39 |
| ▸ | CHRND | Q07001 | 1/20 | 0.39 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6190438 | 0.86 | CHRNB2 (0.68) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL25614895 | 0.83 | CHRNA3 (0.50) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA1 | |
| SCHEMBL25614893 | 0.83 | CHRNA3 (0.50) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA1 | |
| SCHEMBL6189360 | 0.80 | CHRNB2 (0.58) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL651528 | 0.80 | CHRNB2 (0.61) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL650032 | 0.79 | CHRNB2 (0.60) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL25614277 | 0.78 | CHRNB2 (0.46) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL30811721 | 0.77 | CHRNB2 (0.47) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA1 | |
| SCHEMBL29108032 | 0.77 | CHRNB2 (0.47) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA1 | |
| SCHEMBL29108020 | 0.77 | CHRNB2 (0.47) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104209-A1 | METTL3 INHIBITOR COMPOUND | 上海昂阔医药有限公司 | 2023-06-15 | — | — | WO | disclosed |