Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 3/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | MVD | P53602 | 2/20 | 0.35 |
| ▸ | TPI1 | P60174 | 1/20 | 0.33 |
| ▸ | PPIP5K2 | O43314 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.33 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.33 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10722044 | 0.80 | LPAR3 (0.41) | ALDH1A1TPI1PPIP5K2LPAR3LPAR1 | |
| SCHEMBL105467 | 0.76 | KDM5A (0.48) | KDM5AKDM4CALDH1A1ALDH2MEN1 | |
| SCHEMBL6560988 | 0.76 | KDM5A (0.53) | KDM5AKDM4CALDH1A1ALDH2MEN1 | |
| Hydrochloric Acid SCHEMBL866233 | 0.74 | KDM5A (0.47) | KDM5AKDM4CALDH1A1ALDH2MEN1 | |
| SCHEMBL11587066 | 0.74 | KDM5A (0.47) | KDM5AKDM4CALDH1A1ALDH2MEN1 | |
| SCHEMBL8988089 | 0.74 | KDM5A (0.52) | KDM5AKDM4CALDH1A1ALDH2MEN1 | |
| SCHEMBL8204357 | 0.74 | KDM5A (0.47) | KDM5AKDM4CALDH1A1ALDH2MEN1 | |
| SCHEMBL30381417 | 0.72 | KDM5A (0.46) | KDM5AKDM4CALDH1A1ALDH2GAA | |
| SCHEMBL1368442 | 0.71 | TPI1 (0.39) | TPI1LPAR3LPAR1LPAR2PGK1 | |
| SCHEMBL25614400 | 0.70 | ALDH1A1 (0.42) | ALDH1A1ALDH2MVDTPI1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102529-A1 | THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION | GILEAD SCIENCES, INC. (US) | 2023-06-08 | — | — | WO | disclosed |