Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MVD | P53602 | 1/20 | 0.32 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.30 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.30 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.30 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.30 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.30 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.30 |
| ▸ | TPI1 | P60174 | 1/20 | 0.30 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25762731 | 0.85 | KDM4C (0.34) | ALDH1A1ALDH2MVD | |
| SCHEMBL25614399 | 0.84 | MMP1 (0.37) | MMP1MMP2MMP3MMP8LMNA | |
| SCHEMBL26178813 | 0.82 | KDM4C (0.35) | — | |
| SCHEMBL20165514 | 0.78 | ALDH1A1 (0.52) | ALDH1A1ALDH2LMNA | |
| SCHEMBL25762156 | 0.75 | KDM4C (0.33) | ALDH1A1ALDH2 | |
| SCHEMBL25021047 | 0.73 | LPAR3 (0.34) | MMP1MMP2MMP3MMP8MVD | |
| SCHEMBL25787113 | 0.73 | KDM4C (0.35) | — | |
| SCHEMBL25762158 | 0.72 | MVD (0.35) | MVD | |
| SCHEMBL38659925 | 0.72 | MVD (0.33) | MVD | |
| SCHEMBL25614390 | 0.70 | KDM5A (0.37) | ALDH1A1ALDH2MMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102529-A1 | THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION | GILEAD SCIENCES, INC. (US) | 2023-06-08 | — | — | WO | disclosed |