Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIPK2 | Q9H2X6 | 3/20 | 0.67 |
| ▸ | LATS1 | O95835 | 5/20 | 0.55 |
| ▸ | LATS2 | Q9NRM7 | 4/20 | 0.55 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20704257 | 1.00 | HIPK2 (0.67) | HIPK2LATS1LATS2ELANEMEN1 | |
| SCHEMBL30464331 | 1.00 | HIPK2 (0.67) | HIPK2LATS1LATS2ELANEMEN1 | |
| SCHEMBL25224436 | 0.99 | HIPK2 (0.65) | HIPK2LATS1LATS2ELANEMEN1 | |
| SCHEMBL30464322 | 0.99 | HIPK2 (0.65) | HIPK2LATS1LATS2ELANEMEN1 | |
| SCHEMBL25616655 | 0.86 | HIPK2 (0.60) | HIPK2LATS1LATS2MEN1KMT2A | |
| SCHEMBL30464329 | 0.85 | HIPK2 (0.58) | HIPK2LATS1LATS2KMT2ATDP1 | |
| SCHEMBL20704184 | 0.85 | HIPK2 (0.58) | HIPK2LATS1LATS2KMT2ATDP1 | |
| SCHEMBL20704143 | 0.80 | HIPK2 (1.00) | HIPK2LATS1LATS2 | |
| SCHEMBL20704145 | 0.80 | HIPK2 (1.00) | HIPK2LATS1LATS2 | |
| SCHEMBL20704183 | 0.80 | HIPK2 (1.00) | HIPK2LATS1LATS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192621-A1 | Anti-Cancer/Anti-Fibrosis Compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192621-A1 | Anti-Cancer/Anti-Fibrosis Compounds | CCL11, MMP1, HDGF | HIPK2 2797/4885LATS1 2561/4885LATS2 2077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.