Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 7/20 | 0.37 |
| ▸ | RORC | P51449 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 9/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2522496 | 0.81 | CSNK1D (0.47) | CSNK1DCSNK1EKDM4ETHRBRORC | |
| SCHEMBL2523005 | 0.75 | THRB (0.42) | CSNK1DCSNK1EKDM4ETHRBMAPT | |
| SCHEMBL2522815 | 0.74 | CSNK1D (0.44) | CSNK1DCSNK1EKDM4EMAPT | |
| SCHEMBL26783498 | 0.67 | CSNK1D (0.39) | CSNK1DCSNK1EKDM4ERORCNPC1 | |
| SCHEMBL18115090 | 0.67 | CSNK1D (0.48) | CSNK1DCSNK1ETHRBRORCTGFBR1 | |
| SCHEMBL18114976 | 0.66 | TGFBR1 (0.36) | CSNK1DCSNK1EKDM4ETHRBMAPT | |
| SCHEMBL18114967 | 0.66 | TGFBR1 (0.48) | THRBMAPTTGFBR1MAPK14 | |
| SCHEMBL24194909 | 0.66 | MPO (0.44) | CSNK1DCSNK1EMAPK14PDE4B | |
| SCHEMBL30305970 | 0.66 | MPO (0.43) | CSNK1DCSNK1EKDM4ERORCMAPT | |
| SCHEMBL24195522 | 0.66 | MPO (0.43) | CSNK1DCSNK1EKDM4ERORCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2556073-B1 | BICYCLIC PYRIDINYL PYRAZOLES | BAYER IP GMBH (DE) | 2014-07-23 | — | — | EP | disclosed |
| EP-2556073-A1 | BICYCLIC PYRIMIDINYL PYRAZOLES | Bayer Intellectual Property GmbH (DE) | 2013-02-13 | — | — | EP | disclosed |
| WO-2011124539-A1 | BICYCLIC PYRIMIDINYL PYRAZOLES | BAYER CROPSCIENCE AG (DE) | 2011-10-13 | — | — | WO | disclosed |