Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26389476 | 0.84 | — | — | |
| SCHEMBL12299841 | 0.82 | HTT (0.37) | HTTSMN1; SMN2L3MBTL1COMTALDH1A1 | |
| SCHEMBL26388989 | 0.80 | HTT (0.33) | HTTSMN1; SMN2L3MBTL1COMTALDH1A1 | |
| SCHEMBL26067012 | 0.79 | HDAC9 (0.30) | — | |
| SCHEMBL23808019 | 0.78 | RECQL (0.35) | HTTSMN1; SMN2L3MBTL1COMTALDH1A1 | |
| SCHEMBL15071415 | 0.78 | HTT (0.35) | HTTSMN1; SMN2L3MBTL1COMTALDH1A1 | |
| SCHEMBL29911994 | 0.78 | NPC1 (0.47) | HTTSMN1; SMN2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL18330127 | 0.74 | SMN1; SMN2 (0.39) | HTTSMN1; SMN2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL18330041 | 0.73 | KLKB1 (0.39) | HTTSMN1; SMN2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL1871681 | 0.73 | L3MBTL1 (0.40) | HTTSMN1; SMN2L3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167062-A1 | AMIDE COMPOUND CONTAINING SUBSTITUTED ACETOPHENONE STRUCTURAL FRAGMENTS AND PREPARATION METHOD AND APPLICATION THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167062-A1 | AMIDE COMPOUND CONTAINING SUBSTITUTED ACETOPHENONE STRUCTURAL FRAGMENTS AND PREPARATION METHOD AND APPLICATION THEREOF | AADAC, AAK1, ACLY | HTT 2444/4885SMN1; SMN2 3761/4885L3MBTL1 3061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.