Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24014930 | 0.84 | SMN1; SMN2 (0.40) | SMN1; SMN2HTTRAB9ANPC1L3MBTL1 | |
| SCHEMBL1586647 | 0.80 | ALDH1A1 (0.33) | SMN1; SMN2HTTRAB9ANPC1L3MBTL1 | |
| SCHEMBL16937261 | 0.80 | RAB9A (0.30) | SMN1; SMN2RAB9AL3MBTL1DUSP3 | |
| Hydrazine SCHEMBL28089137 | 0.77 | ERN1 (0.31) | HTTMAPTALDH1A1 | |
| SCHEMBL28821668 | 0.77 | L3MBTL1 (0.36) | SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL25618890 | 0.74 | HTT (0.36) | SMN1; SMN2HTTNPC1L3MBTL1KDM4E | |
| SCHEMBL2513813 | 0.74 | SMN1; SMN2 (0.61) | SMN1; SMN2HTTRAB9ANPC1L3MBTL1 | |
| SCHEMBL26388989 | 0.74 | HTT (0.33) | SMN1; SMN2HTTNPC1L3MBTL1KDM4E | |
| SCHEMBL24014929 | 0.74 | SMN1; SMN2 (0.43) | SMN1; SMN2HTTRAB9ANPC1L3MBTL1 | |
| SCHEMBL18464451 | 0.73 | ALDH1A1 (0.48) | SMN1; SMN2HTTRAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312161-B1 | METHOD FOR PREPARING PYRAZOLECARBOXYLIC ACID DERIVATIVE, AND INTERMEDIATE THEREOF | ZHEJIANG YONGTAI TECHNOLOGY CO LTD (CN) | 2020-11-04 | — | — | EP | disclosed |
| EP-3312161-B1 | METHOD FOR PREPARING PYRAZOLECARBOXYLIC ACID DERIVATIVE, AND INTERMEDIATE THEREOF | ZHEJIANG YONGTAI TECHNOLOGY CO LTD (CN) | 2020-11-04 | — | — | EP | disclosed |
| CN-110511216-A | Isoxazoline derivative and its application in agricultural | DONGGUAN DONGYANGGUANG PESTICIDE RES AND DEVELOPMENT CO LTD | 2019-11-29 | — | — | CN | disclosed |
| US-10407413-B2 | Method for preparing pyrazolecarboxylic acid derivative, and intermediate thereof | ZHEJIANG YONGTAI TECHNOLOGY CO., LTD. (CN) | 2019-09-10 | — | — | US | disclosed |
| US-10407413-B2 | Method for preparing pyrazolecarboxylic acid derivative, and intermediate thereof | ZHEJIANG YONGTAI TECHNOLOGY CO., LTD. (CN) | 2019-09-10 | — | — | US | disclosed |
| US-20180194753-A1 | METHOD FOR PREPARING PYRAZOLECARBOXYLIC ACID DERIVATIVE, AND INTERMEDIATE THEREOF | ZHEJIANG YONGTAI TECHNOLOGY CO., LTD (CN) | 2018-07-12 | — | — | US | disclosed |
| US-20180194753-A1 | METHOD FOR PREPARING PYRAZOLECARBOXYLIC ACID DERIVATIVE, AND INTERMEDIATE THEREOF | ZHEJIANG YONGTAI TECHNOLOGY CO., LTD (CN) | 2018-07-12 | — | — | US | disclosed |
| US-20180194753-A1 | METHOD FOR PREPARING PYRAZOLECARBOXYLIC ACID DERIVATIVE, AND INTERMEDIATE THEREOF | ZHEJIANG YONGTAI TECHNOLOGY CO., LTD (CN) | 2018-07-12 | — | — | US | disclosed |
| EP-3312161-A1 | METHOD FOR PREPARING PYRAZOLECARBOXYLIC ACID DERIVATIVE, AND INTERMEDIATE THEREOF | Zhejiang Yongtai Technology Co., Ltd. (CN) | 2018-04-25 | — | — | EP | disclosed |
| EP-3312161-A1 | METHOD FOR PREPARING PYRAZOLECARBOXYLIC ACID DERIVATIVE, AND INTERMEDIATE THEREOF | Zhejiang Yongtai Technology Co., Ltd. (CN) | 2018-04-25 | — | — | EP | disclosed |
| CN-104945325-B | A kind of preparation method of pyrazole carboxylic acid derivant | 浙江永太科技股份有限公司 | 2017-04-05 | — | — | CN | disclosed |
| CN-104945387-B | Intermediate for preparing pyrazol formic acid derivative | 浙江永太科技股份有限公司 | 2017-03-22 | — | — | CN | disclosed |
| WO-2016202254-A1 | METHOD FOR PREPARING PYRAZOLECARBOXYLIC ACID DERIVATIVE, AND INTERMEDIATE THEREOF | 浙江永太科技股份有限公司 | 2016-12-22 | — | — | WO | disclosed |
| CN-104945325-A | Preparation method for pyrazolecarboxylic acid derivative | ZHEJIANG YONGTAI TECHNOLOGY CO LTD | 2015-09-30 | — | — | CN | disclosed |
| CN-104945387-A | Intermediate for preparing pyrazol formic acid derivative | ZHEJIANG YONGTAI TECHNOLOGY CO LTD | 2015-09-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180194753-A1 | METHOD FOR PREPARING PYRAZOLECARBOXYLIC ACID DERIVATIVE, AND INTERMEDIATE THEREOF | CYP3A5, CYP3A43, PGD | SMN1; SMN2 4615/4885HTT 3680/4885RAB9A 2508/4885 |
| US-10407413-B2 | Method for preparing pyrazolecarboxylic acid derivative, and intermediate thereof | CYP3A5, CYP3A43, PGD | SMN1; SMN2 4615/4885HTT 3680/4885RAB9A 2508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.