Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 16/20 | 0.52 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25598440 | 0.83 | FFAR1 (0.53) | FFAR1PPARDLMNA | |
| SCHEMBL25617585 | 0.81 | AKR1C3 (0.47) | FFAR1PPARDLMNA | |
| SCHEMBL8251009 | 0.80 | FFAR1 (0.65) | FFAR1PPARDPTGDR2LMNARAB9A | |
| SCHEMBL654293 | 0.77 | LMNA (0.69) | FFAR1LMNA | |
| SCHEMBL30024728 | 0.77 | LMNA (0.69) | FFAR1LMNA | |
| SCHEMBL23380683 | 0.76 | DHODH (0.55) | — | |
| SCHEMBL20442448 | 0.76 | KAT6A (0.39) | FFAR1 | |
| SCHEMBL13618613 | 0.76 | ACHE (0.52) | FFAR1 | |
| SCHEMBL26730009 | 0.75 | HPGD (0.51) | FFAR1LMNA | |
| SCHEMBL14066555 | 0.73 | FFAR1 (0.54) | FFAR1PPARDPTGDR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3814331-B9 | NOVEL LXR MODULATORS WITH BICYCLIC CORE MOIETY | ORSOBIO INC (US) | 2023-08-09 | — | — | EP | disclosed |
| EP-3814331-B1 | NOVEL LXR MODULATORS WITH BICYCLIC CORE MOIETY | ORSOBIO INC (US) | 2023-06-14 | — | — | EP | disclosed |