SCHEMBL25619355

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1008067	0.89	MAPT (0.59)	EPHX2MAPTRXFP1FFAR1FOLH1
	SCHEMBL5508985	0.89	MAPT (0.59)	EPHX2MAPTRXFP1FFAR1FOLH1
	SCHEMBL2871485	0.89	MAPT (0.59)	EPHX2MAPTRXFP1FFAR1FOLH1
	SCHEMBL25238062	0.89	CA1 (0.50)	EPHX2TRPA1MMP3MMP9MMP8
	SCHEMBL2867823	0.89	MAPT (0.59)	EPHX2MAPTRXFP1FFAR1FOLH1
	SCHEMBL23117118	0.89	CA1 (0.50)	EPHX2TRPA1MMP3MMP9MMP8
	SCHEMBL830483	0.89	MAPT (0.59)	EPHX2MAPTRXFP1FFAR1FOLH1
	SCHEMBL19032486	0.89	CA1 (0.50)	EPHX2TRPA1MMP3MMP9MMP8
	SCHEMBL1007119	0.89	MAPT (0.59)	EPHX2MAPTRXFP1FFAR1FOLH1
	SCHEMBL8984468	0.89	MAPT (0.59)	EPHX2MAPTRXFP1FFAR1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.