SCHEMBL25620243

SCHEMBL25620243

NC(/C=N/N=C/C(N)c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.48
F2 P00734 1/20 0.48
HTR2A P28223 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
ADRA2A P08913 1/20 0.38
ADRA2C P18825 1/20 0.38
LMNA P02545 1/20 0.38
HIF1A Q16665 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28638696 0.81 DPP4 (0.44) DPP4F2ADRA2AADRA2CLMNA
SCHEMBL23339919 0.81 DPP4 (0.44) DPP4F2TAAR1ADRA2AADRA2C
SCHEMBL27501005 0.81 DPP4 (0.44) DPP4F2ADRA2AADRA2CLMNA
SCHEMBL7500324 0.76 DPP4 (0.39) DPP4F2ADRA2AADRA2CLMNA
SCHEMBL38740 0.72 DPP4 (0.50) DPP4F2HTR2ATAAR1ADRA2A
SCHEMBL1534125 0.72 DPP4 (0.50) DPP4F2HTR2ATAAR1ADRA2A
SCHEMBL17286844 0.72 DPP4 (0.50) DPP4F2HTR2ATAAR1ADRA2A
SCHEMBL6963122 0.72 DPP4 (0.50) DPP4F2HTR2ATAAR1ADRA2A
SCHEMBL1683556 0.72 DPP4 (0.50) DPP4F2HTR2ATAAR1ADRA2A
SCHEMBL1036921 0.72 DPP4 (0.50) DPP4F2HTR2ATAAR1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023114453-A1 PHENYLETHYLIDENEHYDRAZINE DIMERS AND METHODS OF USING SAME Neurawell Therapeutics (US) 2023-06-22 WO disclosed