Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17456280 | 0.67 | CYP11B2 (0.67) | CYP11B2MEN1GAATHRBKMT2A | |
| SCHEMBL20245828 | 0.59 | MEN1 (0.33) | CYP11B2MEN1GAATHRBKMT2A | |
| SCHEMBL20245714 | 0.58 | MEN1 (0.43) | MEN1GAATHRBKMT2A | |
| SCHEMBL21831990 | 0.54 | CYP11B2 (1.00) | CYP11B2 | |
| SCHEMBL45941 | 0.51 | KDM4E (0.34) | — | |
| SCHEMBL1164553 | 0.51 | KDM4E (0.34) | — | |
| SCHEMBL6618 | 0.51 | — | — | |
| SCHEMBL1343696 | 0.51 | KDM4E (0.34) | — | |
| SCHEMBL16146464 | 0.50 | — | — | |
| SCHEMBL20245540 | 0.50 | MEN1 (0.57) | MEN1GAATHRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114170-A1 | ALDOSTERONE SYNTHASE INHIBITORS FOR TREATING CHRONIC KIDNEY DISEASE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-06-22 | — | — | WO | disclosed |