Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1030522 | 0.88 | ACHE (0.46) | MAPK1MEN1KMT2AACHEESR2 | |
| SCHEMBL1030521 | 0.88 | ACHE (0.46) | MAPK1MEN1KMT2AACHEESR2 | |
| SCHEMBL21343948 | 0.85 | GPR119 (0.48) | MAPK1ACHEESR2NR1H2GPR119 | |
| SCHEMBL12266171 | 0.81 | ACHE (0.44) | MAPK1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL2397980 | 0.81 | ACHE (0.44) | MAPK1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL1473227 | 0.80 | GPR119 (0.51) | MAPK1ESR2NR1H2GPR119PDK4 | |
| SCHEMBL25275525 | 0.80 | ESR2 (0.47) | MAPK1ALDH1A1MAPTACHEESR2 | |
| SCHEMBL6573258 | 0.80 | ESR2 (0.47) | MAPK1ALDH1A1MAPTACHEESR2 | |
| SCHEMBL15459811 | 0.80 | ESR2 (0.47) | MAPK1ALDH1A1MAPTACHEESR2 | |
| SCHEMBL6573257 | 0.80 | ESR2 (0.47) | MAPK1ALDH1A1MAPTACHEESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104178-A1 | PROTEIN KINASE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 山东绿叶制药有限公司 | 2023-06-15 | — | — | WO | disclosed |