Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | ULK1 | O75385 | 4/20 | 0.37 |
| ▸ | PIP4K2A | P48426 | 2/20 | 0.37 |
| ▸ | PIP4K2B | P78356 | 2/20 | 0.37 |
| ▸ | IKBKB | O14920 | 2/20 | 0.35 |
| ▸ | CHUK | O15111 | 2/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.34 |
| ▸ | FEN1 | P39748 | 3/20 | 0.33 |
| ▸ | BPTF | Q12830 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25625193 | 0.87 | ULK1 (0.36) | NR3C1PGRNR3C2ARULK1 | |
| SCHEMBL25626046 | 0.82 | JAK1 (0.40) | ULK1ALOX5APJAK2BRD4 | |
| SCHEMBL25625104 | 0.80 | ULK1 (0.45) | ULK1FEN1BPTFCDK8PIK3CA | |
| SCHEMBL25613055 | 0.79 | BPTF (0.36) | NR3C1PGRNR3C2ARULK1 | |
| SCHEMBL24005918 | 0.78 | NR3C1 (0.44) | NR3C1PGRNR3C2ARULK1 | |
| SCHEMBL25625108 | 0.77 | PIK3C3 (0.43) | ULK1TGFBR1FEN1CDK8 | |
| SCHEMBL25625191 | 0.75 | RIPK1 (0.38) | ULK1FEN1CDK8 | |
| SCHEMBL25625190 | 0.74 | CDK8 (0.37) | ULK1TGFBR1FEN1CDK8BRD4 | |
| SCHEMBL25613029 | 0.74 | FEN1 (0.39) | ULK1FEN1CDK8PIK3CABRD4 | |
| SCHEMBL25625964 | 0.73 | ULK1 (0.48) | ULK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159527-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON BIOSCIENCES, LTD. (CN) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159527-A1 | COMPOUNDS AS BCL-2 INHIBITORS | BCL2, BCL2L2, BCL2L1 | NR3C1 4345/4885PGR 2286/4885NR3C2 3867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.