Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 8/20 | 0.52 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.52 |
| ▸ | JAK3 | P52333 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KHK | P50053 | 1/20 | 0.43 |
| ▸ | STK4 | Q13043 | 1/20 | 0.42 |
| ▸ | STK3 | Q13188 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | TTK | P33981 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25613151 | 0.82 | PIK3CA (0.49) | PIK3CAPIK3R1JAK3MTORPOLB | |
| SCHEMBL16835984 | 0.73 | PIK3CA (0.48) | PIK3CAPIK3R1JAK3MTORALDH1A1 | |
| SCHEMBL29947184 | 0.73 | KDM4E (0.67) | PIK3CAALDH1A1HPGDPOLBMAPT | |
| SCHEMBL29086584 | 0.72 | PIK3CA (0.54) | PIK3CAPIK3R1MTORSTK3LRRK2 | |
| SCHEMBL5413458 | 0.72 | PIK3CA (0.50) | PIK3CAPIK3R1JAK3MTORPOLB | |
| SCHEMBL30762501 | 0.72 | KMT2A (0.57) | PIK3CAALDH1A1HPGDPOLBMAPT | |
| SCHEMBL856151 | 0.72 | PIK3CA (0.51) | PIK3CAPIK3R1JAK3MTORPOLB | |
| SCHEMBL1360345 | 0.70 | PIK3CA (0.58) | PIK3CAPIK3R1JAK3MTORALDH1A1 | |
| SCHEMBL20369843 | 0.69 | ALDH1A1 (0.54) | ALDH1A1HPGDKHKPOLBMAPT | |
| SCHEMBL31128346 | 0.69 | KDM4E (0.47) | ALDH1A1HPGDKHKPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159527-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON BIOSCIENCES, LTD. (CN) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159527-A1 | COMPOUNDS AS BCL-2 INHIBITORS | BCL2, BCL2L2, BCL2L1 | PIK3CA 1141/4885PIK3R1 254/4885JAK3 3456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.